Ta-Chen Wu, Ph.D.

Affiliations: 
2003 University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Pharmacy
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Win L. Chiou grad student 2003 University of Illinois at Chicago, Health Sciences Center
 (Intestinal carrier -mediated uptake and efflux of furosemide, a classical paracellular transport marker.)
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Publications

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Chiou WL, Ma C, Wu TC, et al. (2003) Unexpected lack of effect of the rifampin-induced P-glycoprotein on the oral bioavailability of its substrate, talinolol, in humans: implication in phenotyping. Journal of Pharmaceutical Sciences. 92: 4-7; discussion 8-9
Wu TC, Ma C, Jeong H, et al. (2002) Comparison of gastrointestinal absorption between human and rat: the role of intestinal absorptive surface area and unstirred aqueous layer(1). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 40: 1901-2; author reply
Wu TC, Ma C, Jeong H, et al. (2002) Comparison of gastrointestinal absorption between human and rat: the role of intestinal absorptive surface area and unstirred aqueous layer. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 40: 1727-8
Chiou WL, Wu TC, Ma C, et al. (2002) Enhanced oral bioavailability of docetaxel by coadministration of cyclosporine: quantitation and role of P-glycoprotein. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 20: 1951-2; author reply
Chiou WL, Jeong HY, Wu TC, et al. (2001) Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization. Clinical Pharmacology and Therapeutics. 70: 305-10
Chung SM, Park EJ, Swanson SM, et al. (2001) Profound effect of plasma protein binding on the polarized transport of furosemide and verapamil in the Caco-2 model. Pharmaceutical Research. 18: 544-7
Chiou WL, Chung SM, Wu TC, et al. (2001) A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans. International Journal of Clinical Pharmacology and Therapeutics. 39: 93-101
Chiou WL, Ma C, Chung SM, et al. (2001) An alternative hypothesis to involvement of intestinal P-glycoprotein as the cause for digoxin oral bioavailability enhancement by talinolol. Clinical Pharmacology and Therapeutics. 69: 79-81
Chiou WL, Ma C, Chung SM, et al. (2000) Similarity in the linear and non-linear oral absorption of drugs between human and rat. International Journal of Clinical Pharmacology and Therapeutics. 38: 532-9
Chiou WL, Chung SM, Wu TC. (2000) Potential role of P-glycoprotein in affecting hepatic metabolism of drugs. Pharmaceutical Research. 17: 903-5
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