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Hanlin Gao, Ph.D.

Affiliations: 
2001 Ohio State University, Columbus, Columbus, OH 
Area:
Biochemistry, Pharmacology, Oncology
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Robert M. Snapka grad student 2001 Ohio State
 (Characterization of cell lines resistant to topoisomerase targeting drugs and mechanistic studies of quinoxaline solid tumor drugs: A new chemical class of topoisomerase II poisons.)

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Kalvala A, Wallet P, Yang L, et al. (2019) Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS. Journal of Clinical Medicine. 8
Li Y, Wu X, Gao H, et al. (2015) PIWI-interacting RNAs are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer specific survival. Molecular Medicine (Cambridge, Mass.)
Hu Z, Wang J, Yao T, et al. (2013) Identification of novel mutations of TP53, ALK and RET gene in metastatic thymic squamous cell carcinoma and its therapeutic implication. Lung Cancer (Amsterdam, Netherlands). 81: 27-31
Zhang K, Chu K, Wu X, et al. (2013) Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma. Cancer Research. 73: 1298-307
Li Y, Wu X, Gao H, et al. (2013) Abstract LB-247: 5′-tRFHis-GTG, a novel tRNA-derived novel miRNA-like small non-coding RNA, aberrantly expressed in metastatic renal cell carcinoma by promoting tumor cell proliferation, migration and invasion. Cancer Research. 73
Weng L, Wu X, Gao H, et al. (2010) MicroRNA profiling of clear cell renal cell carcinoma by whole-genome small RNA deep sequencing of paired frozen and formalin-fixed, paraffin-embedded tissue specimens. The Journal of Pathology. 222: 41-51
Zhang J, Zhou C, Yin Y, et al. (2006) Detection of Known Mutations with DNA Polymerases: Its Pharmacogenetic Applications Current Pharmacogenomics. 4: 121-131
Gao H, Yamasaki EF, Chan KK, et al. (2003) DNA sequence specificity for topoisomerase II poisoning by the quinoxaline anticancer drugs XK469 and CQS. Molecular Pharmacology. 63: 1382-8
Huang KC, Gao H, Yamasaki EF, et al. (2001) Topoisomerase II poisoning by ICRF-193. The Journal of Biological Chemistry. 276: 44488-94
Snapka RM, Gao H, Grabowski DR, et al. (2001) Cytotoxic mechanism of XK469: resistance of topoisomerase IIbeta knockout cells and inhibition of topoisomerase I. Biochemical and Biophysical Research Communications. 280: 1155-60
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