J. William Lown

University of Alberta, Edmonton, Alberta, Canada 
"J. William Lown"
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Peters JH, Gordon GR, Kashiwase D, et al. (1986) Redox activities of antitumor anthracyclines determined by microsomal oxygen consumption and assays for superoxide anion and hydroxyl radical generation. Biochemical Pharmacology. 35: 1309-23
Lown JW, Morgan AR, Yen SF, et al. (1985) Characteristics of the binding of the anticancer agents mitoxantrone and ametantrone and related structures to deoxyribonucleic acids. Biochemistry. 24: 4028-35
Lown JW, Joshua AV, Lee JS. (1982) Molecular mechanisms of binding and single-strand scission of DNA by the antitumor antibiotics saframycins A and C Biochemistry. 21: 419-428
Lown JW, Joshua AV. (1982) Bleomycin models. Haemin–acridines which bind to DNA and cause oxygen-dependent scission Journal of the Chemical Society, Chemical Communications. 1298-1300
Lown JW, Joshua AV, McLaughlin LW. (1980) Noval antitumor nitrosoureas and related compounds and their reactions with DNA. Journal of Medicinal Chemistry. 23: 798-805
Lown JW, McLaughlin LW. (1979) Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Nature of the chemical reactions with deoxyribonucleic acid. Biochemical Pharmacology. 28: 2123-8
Lown JW, McLaughlin LW. (1979) Nitrosourea-induced DNA single-strand breaks. Biochemical Pharmacology. 28: 1631-8
Lown JW, McLaughlin LW, Plambeck JA. (1979) Mechanism of action of 2-haloethylnitrosoureas on deoxyribonucleic acid. Nature of the intermediates from nitrosourea decomposition. Biochemical Pharmacology. 28: 2115-21
Lown JW, Gunn BC, Majumdar KC, et al. (1979) Synthesis of potential DNA bisintercalative agents of the phenanthridinium class Canadian Journal of Chemistry. 57: 2305-2313
Lown JW, Gunn BC, Chang RY, et al. (1978) Bis-intercalative binding to DNA of novel bis(10-methyl)acridinium chlorides and its dependence on chain length of linker. Canadian Journal of Biochemistry. 56: 1006-15
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