Irving W. Wainer

Affiliations: 
McGill University, Montreal, QC, Canada 
Area:
Analytical Chemistry, Pharmaceutical Chemistry
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"Irving Wainer"
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Publications

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Wnorowski A, Dudzik D, Bernier M, et al. (2022) Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β adrenergic agonist. Scientific Reports. 12: 3618
Woo AY, Ge XY, Pan L, et al. (2019) Discovery of β-arrestin-biased β-adrenoceptor agonists from 2-amino-2-phenylethanol derivatives. Acta Pharmacologica Sinica
Faccio AT, Ruperez FJ, Singh NS, et al. (2018) Stereochemical and structural effects of (2R,6R)-hydroxynorketamine on the mitochondrial metabolome in PC-12 cells. Biochimica Et Biophysica Acta
Bernier M, Catazaro J, Singh NS, et al. (2017) GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts. International Journal of Cancer
Wnorowski A, Such J, Paul RK, et al. (2017) Concurrent activation of β2-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells. Cellular Signalling
Can A, Zanos P, Moaddel R, et al. (2016) Effects of ketamine and ketamine metabolites on evoked striatal dopamine release, dopamine receptors, and monoamine transporters. The Journal of Pharmacology and Experimental Therapeutics
Singh NS, Bernier M, Wainer IW. (2016) Selective GPR55 antagonism reduces chemoresistance in cancer cells. Pharmacological Research
Zanos P, Moaddel R, Morris PJ, et al. (2016) NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature
Singh NS, Rutkowska E, Plazinska A, et al. (2016) Ketamine Metabolites Enantioselectively Decrease Intracellular D-Serine Concentrations in PC-12 Cells. Plos One. 11: e0149499
Moaddel R, Sanghvi M, Ramamoorthy A, et al. (2016) Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats. Journal of Pharmaceutical and Biomedical Analysis
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