Karen S. Anderson
Affiliations: | Pharmacology | Yale University School of Medicine, New Haven, CT |
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Sign in to add trainee| Kathleen M. Frey | post-doc | Yale School of Medicine | |
| Christal D. Sohl | post-doc | 2010-2015 | Yale School of Medicine |
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| Prucha GR, Henry S, Hollander K, et al. (2023) Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase. European Journal of Medicinal Chemistry. 262: 115894 |
| Hollander K, Chan AH, Frey KM, et al. (2023) Exploring Novel HIV-1 Reverse Transcriptase Inhibitors with Drug Resistant Mutants: A Double Mutant Surprise. Protein Science : a Publication of the Protein Society. e4814 |
| Carter ZJ, Hollander K, Spasov KA, et al. (2023) Design, synthesis, and biological testing of biphenylmethyloxazole inhibitors targeting HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry Letters. 84: 129216 |
| Gannam ZTK, Jamali H, Kweon OS, et al. (2022) Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors. European Journal of Medicinal Chemistry. 243: 114712 |
| Frey KM, Bertoletti N, Chan AH, et al. (2022) Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Frontiers in Molecular Biosciences. 9: 805187 |
| Beloor J, Kudalkar SN, Buzzelli G, et al. (2022) Long-acting and extended-release implant and nanoformulations with a synergistic antiretroviral two-drug combination controls HIV-1 infection in a humanized mouse model. Bioengineering & Translational Medicine. 7: e10237 |
| Deshmukh MG, Ippolito JA, Zhang CH, et al. (2021) Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease. Structure (London, England : 1993) |
| Ippolito JA, Niu H, Bertoletti N, et al. (2021) Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. Acs Medicinal Chemistry Letters. 12: 249-255 |
| Bertoletti N, Chan AH, Schinazi RF, et al. (2020) Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. Molecules (Basel, Switzerland). 25 |
| Duong VN, Ippolito JA, Chan AH, et al. (2020) Structural Investigation of 2-Naphthyl Phenyl Ether Inhibitors Bound to WT and Y181C Reverse Transcriptase Highlights Key Features of the NNRTI Binding Site. Protein Science : a Publication of the Protein Society |