George C. Prendergast

Lankenau Institute for Medical Research 
Cancer Research
"George Prendergast"
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Thomas S, Prendergast GC. (2023) Gut-brain connections in neurodegenerative disease: immunotherapeutic targeting of Bin1 in inflammatory bowel disease and Alzheimer's disease. Frontiers in Pharmacology. 14: 1183932
Thomas S, Dilbarov N, Kelly J, et al. (2023) Diet effects on colonic health influence the efficacy of Bin1 mAb immunotherapy for ulcerative colitis. Scientific Reports. 13: 11802
Muller AJ, Thomas S, Prendergast GC. (2023) A Brief Overview of Cancer Vaccines. Cancer Journal (Sudbury, Mass.). 29: 34-37
Thomas S, Mercogliano G, Prendergast GC. (2022) Bin1 targeted immunotherapy alters the status of the enteric neurons and the microbiome during ulcerative colitis treatment. Plos One. 17: e0276910
Dey S, Mondal A, DuHadaway JB, et al. (2021) IDO1 Signaling Through GCN2 in a Subpopulation of Gr-1+ Cells Shifts the IFNγ/IL6 Balance to Promote Neovascularization. Cancer Immunology Research
Merlo LMF, DuHadaway JB, Montgomery JD, et al. (2020) Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses. Frontiers in Immunology. 11: 1861
Dey S, Mondal A, DuHadaway JB, et al. (2020) Abstract 1474: IDO1 signaling supports inflammatory neovascularization Cancer Research. 80: 1474-1474
Thomas S, Laury-Kleintop L, Prendergast GC. (2019) Reliable detection of indoleamine 2,3 dioxygenase-1 in murine cells and tissues. Methods in Enzymology. 629: 219-233
Metz R, Smith C, DuHadaway JB, et al. (2019) IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. International Immunology. 31: 181-182
Thomas S, Hoxha K, Tran A, et al. (2019) Bin1 antibody lowers the expression of phosphorylated Tau in Alzheimer's disease. Journal of Cellular Biochemistry
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