Elizabeth J. Little, Ph.D.

Affiliations: 
2003 University of Arizona, Tucson, AZ 
Area:
Molecular Biology, Cell Biology, Genetics
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"Elizabeth Little"
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Parents

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Ted A. Weinert grad student 2003 University of Arizona
 (DNA damage sensors in the checkpoint response.)
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Publications

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Little EJ, Dunten PW, Bitinaite J, et al. (2011) New clues in the allosteric activation of DNA cleavage by SgrAI: structures of SgrAI bound to cleaved primary-site DNA and uncleaved secondary-site DNA. Acta Crystallographica. Section D, Biological Crystallography. 67: 67-74
Park CK, Joshi HK, Agrawal A, et al. (2010) Domain swapping in allosteric modulation of DNA specificity. Plos Biology. 8: e1000554
Little EJ, Babic AC, Horton NC. (2008) Early interrogation and recognition of DNA sequence by indirect readout. Structure (London, England : 1993). 16: 1828-37
Babic AC, Little EJ, Manohar VM, et al. (2008) DNA distortion and specificity in a sequence-specific endonuclease. Journal of Molecular Biology. 383: 186-204
Dunten PW, Little EJ, Gregory MT, et al. (2008) The structure of SgrAI bound to DNA; recognition of an 8 base pair target. Nucleic Acids Research. 36: 5405-16
Little EJ, Horton NC. (2005) DNA-induced conformational changes in type II restriction endonucleases: the structure of unliganded HincII. Journal of Molecular Biology. 351: 76-88
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