Simon J. Sharpe, Ph.D.
Affiliations: | 2002 | The University of Western Ontario (Canada) |
Area:
Biochemistry, Molecular Biology, Cell BiologyGoogle:
"Simon Sharpe"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Chris W.M. Grant | grad student | 2002 | The University of Western Ontario (Canada) | |
| (NMR studies of ErbB transmembrane domains in phospholipid bilayers.) | ||||
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Publications
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| Tran P, Tran HNT, McMahon KL, et al. (2023) Changes in Potency and Subtype Selectivity of Bivalent Na Toxins are Knot-Specific. Bioconjugate Chemistry |
| Parashar A, Gourgas O, Lau K, et al. (2020) Elastin calcification in in vitro models and its prevention by MGP's m3pS peptide. Journal of Structural Biology. 107637 |
| Stone TA, Cole GB, Ravamehr-Lake D, et al. (2019) Positive charge patterning and hydrophobicity of membrane-active antimicrobial peptides as determinants of activity, toxicity, and pharmacokinetic stability. Journal of Medicinal Chemistry |
| Stone TA, Cole GB, Nguyen HQ, et al. (2017) Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides. Bioorganic & Medicinal Chemistry |
| Walsh P, Vanderlee G, Yau J, et al. (2014) The mechanism of membrane disruption by cytotoxic amyloid oligomers formed by prion protein(106-126) is dependent on bilayer composition. The Journal of Biological Chemistry. 289: 10419-30 |
| Reichheld SE, Muiznieks LD, Stahl R, et al. (2014) Conformational transitions of the cross-linking domains of elastin during self-assembly. The Journal of Biological Chemistry. 289: 10057-68 |
| Yau J, Sharpe S. (2012) Structures of amyloid fibrils formed by the prion protein derived peptides PrP(244-249) and PrP(245-250) Journal of Structural Biology. 180: 290-302 |
| Cole G, Simonetti K, Ademi I, et al. (2012) Dimerization of the transmembrane domain of human tetherin in membrane mimetic environments. Biochemistry. 51: 5033-40 |
| Sharpe S, Simonetti K, Yau J, et al. (2011) Solid-state NMR characterization of autofluorescent fibrils formed by the elastin-derived peptide GVGVAGVG Biomacromolecules. 12: 1546-1555 |
| Walsh P, Neudecker P, Sharpe S. (2010) Structural properties and dynamic behavior of nonfibrillar oligomers formed by PrP(106-126) Journal of the American Chemical Society. 132: 7684-7695 |