Isaac Donkor

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry, Organic Chemistry, Pharmacology
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"Isaac Donkor"
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Publications

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Donkor IO, Xu J, Liu J, et al. (2020) Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry. 115433
Sampson JJ, Donkor IO, Huang TL, et al. (2011) Novel piperazine induces apoptosis in U937 cells. International Journal of Biochemistry and Molecular Biology. 2: 78-88
Donkor IO, Korukonda R. (2008) Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position. Bioorganic & Medicinal Chemistry Letters. 18: 4806-8
Donkor IO, Assefa H, Liu J. (2008) Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids. Journal of Medicinal Chemistry. 51: 4346-50
Huang TL, Bacchi CJ, Kode NR, et al. (2007) Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug. International Journal of Antimicrobial Agents. 30: 555-61
Korukonda R, Guan N, Dalton JT, et al. (2006) Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides. Journal of Medicinal Chemistry. 49: 5282-90
Huang TL, Vanden Eynde JJ, Mayence A, et al. (2006) Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners. The Journal of Pharmacy and Pharmacology. 58: 1033-42
Guan N, Korukonda R, Hurh E, et al. (2006) Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. International Journal of Oncology. 29: 655-63
Sanders ML, Donkor IO. (2006) A novel series of urea-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 1965-8
Donkor IO, Li H, Queener SF. (2003) Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines. European Journal of Medicinal Chemistry. 38: 605-11
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