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John C. Drach

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmaceutical Chemistry, Pharmacology
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"John Drach"
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David L. Evers grad student 2002 University of Michigan
Gloria Komazin grad student 2003 University of Michigan

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Publications

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Gentry BG, Bogner E, Drach JC. (2019) Targeting the terminase: An important step forward in the treatment and prophylaxis of human cytomegalovirus infections. Antiviral Research. 161: 116-124
Dittmer A, Woskobojnik I, Adfeldt R, et al. (2016) Tetrahalogenated benzimidazole D-ribonucleosides are active against rat cytomegalovirus. Antiviral Research
Gentry BG, Phan Q, Hall ED, et al. (2015) Human cytomegalovirus resistance to deoxyribosylindole nucleosides maps to a transversion mutation in the terminase subunit-encoding gene UL89. Antimicrobial Agents and Chemotherapy. 59: 226-32
Gentry BG, Drach JC. (2014) Metabolism of cyclopropavir and ganciclovir in human cytomegalovirus-infected cells. Antimicrobial Agents and Chemotherapy. 58: 2329-33
Gentry BG, Vollmer LE, Hall ED, et al. (2013) Resistance of human cytomegalovirus to cyclopropavir maps to a base pair deletion in the open reading frame of UL97. Antimicrobial Agents and Chemotherapy. 57: 4343-8
Li C, Quenelle DC, Prichard MN, et al. (2012) Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir. Bioorganic & Medicinal Chemistry. 20: 2669-74
Zakharova VM, Serpi M, Krylov IS, et al. (2011) Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies. Journal of Medicinal Chemistry. 54: 5680-93
Peterson LW, Kim JS, Kijek P, et al. (2011) Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir. Bioorganic & Medicinal Chemistry Letters. 21: 4045-9
Prichard MN, Frederick SL, Daily S, et al. (2011) Benzimidazole analogs inhibit human herpesvirus 6. Antimicrobial Agents and Chemotherapy. 55: 2442-5
Gentry BG, Gentry SN, Jackson TL, et al. (2011) Phosphorylation of antiviral and endogenous nucleotides to di- and triphosphates by guanosine monophosphate kinase. Biochemical Pharmacology. 81: 43-9
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