Juergen Rohr

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Analytical Chemistry, Biochemistry, Molecular Biology
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"Juergen Rohr"
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Uwe Rix grad student 2003 MUSC
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Publications

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Cui Z, Wang XC, Liu X, et al. (2018) Self-Resistance During Muraymycin Biosynthesis: A Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order. Antimicrobial Agents and Chemotherapy
Gao G, Liu X, Xu M, et al. (2017) Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement. Cell Chemical Biology
Kharel MK, Rohr J. (2012) Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology. Current Opinion in Chemical Biology. 16: 150-61
Kharel MK, Pahari P, Shaaban KA, et al. (2012) Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis. Organic & Biomolecular Chemistry. 10: 4256-65
Nybo SE, Shabaan KA, Kharel MK, et al. (2012) Ketoolivosyl-tetracenomycin C: a new ketosugar bearing tetracenomycin reveals new insight into the substrate flexibility of glycosyltransferase ElmGT. Bioorganic & Medicinal Chemistry Letters. 22: 2247-50
Pahari P, Kharel MK, Shepherd MD, et al. (2012) Enzymatic total synthesis of defucogilvocarcin M and its implications for gilvocarcin biosynthesis. Angewandte Chemie (International Ed. in English). 51: 1216-20
Kharel MK, Nybo SE, Shepherd MD, et al. (2010) Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters. Chembiochem : a European Journal of Chemical Biology. 11: 523-32
Liu T, Kharel MK, Zhu L, et al. (2009) Inactivation of the ketoreductase gilU gene of the gilvocarcin biosynthetic gene cluster yields new analogues with partly improved biological activity. Chembiochem : a European Journal of Chemical Biology. 10: 278-86
Lombó F, Abdelfattah MS, Braña AF, et al. (2009) Elucidation of oxygenation steps during oviedomycin biosynthesis and generation of derivatives with increased antitumor activity. Chembiochem : a European Journal of Chemical Biology. 10: 296-303
Ramos A, Lombó F, Braña AF, et al. (2008) Biosynthesis of elloramycin in Streptomyces olivaceus requires glycosylation by enzymes encoded outside the aglycon cluster. Microbiology (Reading, England). 154: 781-8
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