Xiaohui Wang

Affiliations: 
University of Colorado, Boulder, Boulder, CO, United States 
Area:
opioid, pain, TLRs, neuroinflammation, transmembrane protein
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"Xiaohui Wang"
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Publications

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Gao J, Lin C, Zhang C, et al. (2024) Exploring the Function of (+)-Naltrexone Precursors: Their Activity as TLR4 Antagonists and Potential in Treating Morphine Addiction. Journal of Medicinal Chemistry
Wu S, Zhang C, Wang Y, et al. (2023) Dissecting the species-specific recognition of Neoseptin 3 by TLR4/MD2 molecular dynamics simulations. Physical Chemistry Chemical Physics : Pccp. 25: 13012-13018
Kornilov FD, Shabalkina AV, Lin C, et al. (2023) The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors. Nature Communications. 14: 1503
Wang X, Lin C, Wu S, et al. (2022) Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia. Frontiers in Immunology. 13: 929222
Zhang T, Lin C, Wu S, et al. (2022) ACT001 Inhibits TLR4 Signaling by Targeting Co-Receptor MD2 and Attenuates Neuropathic Pain. Frontiers in Immunology. 13: 873054
Wu S, Lin C, Zhang T, et al. (2022) Pentamidine Alleviates Inflammation and Lipopolysaccharide-Induced Sepsis by Inhibiting TLR4 Activation Targeting MD2. Frontiers in Pharmacology. 13: 835081
Kot EF, Wang Y, Goncharuk SA, et al. (2020) Oligomerization analysis as a tool to elucidate the mechanism of EBV latent membrane protein 1 inhibition by pentamidine. Biochimica Et Biophysica Acta. Biomembranes. 183380
Wang Y, Zhang S, Li H, et al. (2020) Small-Molecule Modulators of Toll-like Receptors. Accounts of Chemical Research
Zhang X, Wang Y, Wang H, et al. (2020) Exploring methamphetamine non-enantioselectively targeting Toll-like receptor 4/myeloid differentiation protein 2 by in silico simulations and wet-lab techniques. Journal of Chemical Information and Modeling
Peng Y, Zhang X, Zhang T, et al. (2019) Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity
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