Cibele S. Pinto, Ph.D.

Affiliations: 
2007 University of Kansas, Lawrence, KS, United States 
Area:
Pharmacology, Molecular Biology
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"Cibele Pinto"
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Parents

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Roland Seifert grad student 2007 University of Kansas
 (Molecular analysis of adenylyl cyclases.)
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Publications

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Pinto CS, Raman A, Reif GA, et al. (2015) Phosphodiesterase Isoform Regulation of Cell Proliferation and Fluid Secretion in Autosomal Dominant Polycystic Kidney Disease. Journal of the American Society of Nephrology : Jasn
Pinto CS, Reif GA, Nivens E, et al. (2012) Calmodulin-sensitive adenylyl cyclases mediate AVP-dependent cAMP production and Cl- secretion by human autosomal dominant polycystic kidney cells. American Journal of Physiology. Renal Physiology. 303: F1412-24
Reif GA, Yamaguchi T, Nivens E, et al. (2011) Tolvaptan inhibits ERK-dependent cell proliferation, Cl⁻ secretion, and in vitro cyst growth of human ADPKD cells stimulated by vasopressin. American Journal of Physiology. Renal Physiology. 301: F1005-13
Pinto C, Lushington GH, Richter M, et al. (2011) Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases. Biochemical Pharmacology. 82: 358-70
Hübner M, Dixit A, Mou TC, et al. (2011) Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate. Molecular Pharmacology. 80: 87-96
Suryanarayana S, Pinto C, Mou TC, et al. (2009) The C1 homodimer of adenylyl cyclase binds nucleotides with high affinity but possesses exceedingly low catalytic activity. Neuroscience Letters. 467: 1-5
Pinto C, Hübner M, Gille A, et al. (2009) Differential interactions of the catalytic subunits of adenylyl cyclase with forskolin analogs. Biochemical Pharmacology. 78: 62-9
Pinto C, Papa D, Hübner M, et al. (2008) Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs. The Journal of Pharmacology and Experimental Therapeutics. 325: 27-36
Lorenz V, Pinto CS, Seifert R. (2007) Complex changes in ecto-nucleoside 5'-triphosphate diphosphohydrolase expression in hypoxanthine phosphoribosyl transferase deficiency. Neuroscience Letters. 420: 6-11
Pinto CS, Seifert R. (2006) Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes. Journal of Neurochemistry. 96: 454-9
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