Larry M. C. Chow
Affiliations: | Hong Kong Polytechnic University (Hong Kong) |
Area:
Pharmaceutical ChemistryGoogle:
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Sign in to add trainee| Tan Weiqi | grad student | 2005 | Hong Kong Polytechnic University (Hong Kong) |
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Publications
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| Dury L, Nasr R, Lorendeau D, et al. (2016) Flavonoid dimers are highly potent killers of multidrug resistant cancer cells overexpressing MRP1. Biochemical Pharmacology |
| Ashok P, Chander S, Chow LM, et al. (2016) Synthesis and in-vitro anti-leishmanial activity of (4-arylpiperazin-1-yl)(1-(thiophen-2-yl)-9H-pyrido[3,4-b]indol-3-yl)methanone derivatives. Bioorganic Chemistry |
| Yang C, Wong IL, Peng K, et al. (2016) Extending the structure-activity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors. European Journal of Medicinal Chemistry. 125: 795-806 |
| Baiceanu E, Nguyen KA, Gonzalez-Lobato L, et al. (2016) 2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2. European Journal of Medicinal Chemistry. 122: 408-418 |
| Yan CS, Wong IL, Chan KF, et al. (2015) A New Class of Safe, Potent, and Specific P-gp Modulator: Flavonoid Dimer FD18 Reverses P-gp-Mediated Multidrug Resistance in Human Breast Xenograft in Vivo. Molecular Pharmaceutics |
| Wang Z, Wong IL, Li FX, et al. (2015) Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors. Bioorganic & Medicinal Chemistry |
| Wong IL, Wang BC, Yuan J, et al. (2015) Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. Journal of Medicinal Chemistry. 58: 4529-49 |
| Loh CC, Suwanarusk R, Lee YQ, et al. (2014) Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. Plos One. 9: e110800 |
| Yang C, Wong IL, Jin WB, et al. (2014) Modification of marine natural product ningalin B and SAR study lead to potent P-glycoprotein inhibitors. Marine Drugs. 12: 5209-21 |
| Zhang N, Zhang Z, Wong IL, et al. (2014) 4,5-Di-substituted benzyl-imidazol-2-substituted amines as the structure template for the design and synthesis of reversal agents against P-gp-mediated multidrug resistance breast cancer cells. European Journal of Medicinal Chemistry. 83: 74-83 |