Judith Pollock Klinman

University of California, Berkeley, Berkeley, CA 
fundamental aspects of enzyme catalysis
"Judith Pollock Klinman"


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Edward R. Thornton grad student 1966 Penn
 (A kinetic study of the hydrolysis and imidazole-catalyzed hydrolysis of substituted benzolimidazoles in light and heavy water)
David Samuel post-doc 1968 Weizmann Institute
Irwin A. Rose research scientist Fox Chase Cancer Center


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Tara Armand research assistant 2014-2016 UC Berkeley (BME Tree)
Advaita Panchagnula research assistant 2016-2017 UC Berkeley
Joanne E. Dove grad student 2000 UC Berkeley
Stephen A. Mills grad student 2001 UC Berkeley
Sean L. Seymour grad student 2001 UC Berkeley
Matthew M. Purdy grad student 2003 UC Berkeley
Olayinka A. Oyeyemi grad student 2008 UC Berkeley
Cindy M. Chang grad student 2009 UC Berkeley
Kevin P. McCusker grad student 2009 UC Berkeley
Zachary D. Nagel grad student 2009 UC Berkeley
Jordan M. RoseFigura grad student 2010 UC Berkeley
Sam H. Shen grad student 2010 UC Berkeley
Marcus A. Strawn grad student 2010 UC Berkeley
Cody A. Carr grad student 2013 UC Berkeley
Marcus Carr grad student 2008-2013 UC Berkeley
Corey W. Meadows grad student 2014 UC Berkeley
Jennifer L. DuBois post-doc UC Berkeley
Eric M. Koehn post-doc UC Berkeley
Shenshen Hu post-doc 2012- UC Berkeley
Emily J Thompson post-doc 2017- UC Berkeley
Wen Zhu post-doc 2017- UC Berkeley
Shuaihua Gao post-doc 2018- UC Berkeley
Jan Paulo Zaragoza post-doc 2018- UC Berkeley
Michael D. Toney post-doc 1993 UC Berkeley
Brian James Bahnson post-doc 1990-1993 UC Berkeley
Amnon Kohen post-doc 1995-1999 UC Berkeley
Michael Knapp post-doc 1998-2002 UC Berkeley
Justine P. Roth post-doc 2000-2003 UC Berkeley
Kristi J. Humphreys post-doc 2002-2007 UC Berkeley
Liviu M. Mirica post-doc 2005-2008 UC Berkeley
Ian Barr post-doc 2013-2017 UC Berkeley
Adam R Offenbacher post-doc 2013-2017 UC Berkeley
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Zhang J, Balsbaugh JL, Gao S, et al. (2020) Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol -methyltransferase reaction. Proceedings of the National Academy of Sciences of the United States of America
Offenbacher AR, Sharma A, Doan PE, et al. (2020) The Soybean Lipoxygenase-Substrate Complex: Correlation between the Properties of Tunneling-Ready States and ENDOR-Detected Structures of Ground States. Biochemistry
Tao L, Zhu W, Klinman JP, et al. (2019) EPR Spectroscopic Identification of the Fe-S Clusters in the SPASM-Domain Containing Radical SAM Enzyme PqqE. Biochemistry
Hu S, Offenbacher AR, Lu ED, et al. (2019) Comparative kinetic isotope effects on first- and second-order rate constants of soybean lipoxygenase variants uncover a substrate-binding network. The Journal of Biological Chemistry
Zaragoza JPT, Nguy A, Minnetian N, et al. (2019) Detecting and Characterizing the Kinetic Activation of Thermal Networks in Proteins: Thermal Transfer from a Distal, Solvent-Exposed Loop to the Active Site in Soybean Lipoxygenase. The Journal of Physical Chemistry. B
Martins AM, Latham JA, Martel PJ, et al. (2019) A two-component protease in with high activity toward the peptide precursor of the redox cofactor pyrroloquinoline quinone. The Journal of Biological Chemistry
Masson GR, Burke JE, Ahn NG, et al. (2019) Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Nature Methods. 16: 595-602
Koehn EM, Latham JA, Armand T, et al. (2019) Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway. Journal of the American Chemical Society
Hu S, Offenbacher AR, Thompson EM, et al. (2019) Biophysical Characterization of a Disabled Double Mutant of Soybean Lipoxygenase: The "Undoing" of Precise Substrate Positioning Relative to Metal Cofactor and an Identified Dynamical Network. Journal of the American Chemical Society
Klinman JP, Offenbacher AR. (2018) Understanding Biological Hydrogen Transfer Through the Lens of Temperature Dependent Kinetic Isotope Effects. Accounts of Chemical Research
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