Mercedes E. Arana, Ph.D.

Affiliations: 
2004 University of Miami, Coral Gables, FL 
Area:
Biochemistry, Molecular Biology
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"Mercedes Arana"
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Parents

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Paul E. Boehmer grad student 2004 University of Miami
 (A repertoire of transactions in the herpes simplex virus type-1 genome.)
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Publications

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Williams JS, Tumbale PP, Arana ME, et al. (2021) High-fidelity DNA ligation enforces accurate Okazaki fragment maturation during DNA replication. Nature Communications. 12: 482
Huang SN, Williams JS, Arana ME, et al. (2016) Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks. The Embo Journal
Arana ME, Potapova O, Kunkel TA, et al. (2011) Kinetic analysis of the unique error signature of human DNA polymerase ν. Biochemistry. 50: 10126-35
García-Ortíz MV, Marsin S, Arana ME, et al. (2011) Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability. Plos Genetics. 7: e1002152
Arana ME, Kunkel TA. (2010) Mutator phenotypes due to DNA replication infidelity. Seminars in Cancer Biology. 20: 304-11
Takata K, Arana ME, Seki M, et al. (2010) Evolutionary conservation of residues in vertebrate DNA polymerase N conferring low fidelity and bypass activity. Nucleic Acids Research. 38: 3233-44
Arana ME, Holmes SF, Fortune JM, et al. (2010) Functional residues on the surface of the N-terminal domain of yeast Pms1. Dna Repair. 9: 448-57
Arana ME, Powell GK, Edwards LL, et al. (2010) Refolding active human DNA polymerase nu from inclusion bodies. Protein Expression and Purification. 70: 163-71
Arana ME, Seki M, Wood RD, et al. (2008) Low-fidelity DNA synthesis by human DNA polymerase theta. Nucleic Acids Research. 36: 3847-56
Kadyrov FA, Holmes SF, Arana ME, et al. (2007) Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. The Journal of Biological Chemistry. 282: 37181-90
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