David F. Savage

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA 
Area:
Biophysics, Synthetic Biology, and Systems Biology
Website:
www.savagelab.org
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"David Savage"
Mean distance: 8.58
 
SNBCP

Parents

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Robert M. Stroud grad student 2002-2007 UCSF
 (Towards membrane protein structure determination.)
Pamela A. Silver post-doc 2007-2011 Harvard Medical School

Children

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Dana C. Nadler grad student 2014 UC Berkeley (BME Tree)
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Publications

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Shams A, Higgins SA, Fellmann C, et al. (2021) Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules. Nature Communications. 12: 5664
Lee TH, Carpenter TS, D'haeseleer P, et al. (2019) Encapsulin carrier proteins for enhanced expression of antimicrobial peptides. Biotechnology and Bioengineering
Kundert K, Lucas JE, Watters KE, et al. (2019) Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs. Nature Communications. 10: 2127
Oakes BL, Fellmann C, Rishi H, et al. (2019) CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification. Cell. 176: 254-267.e16
Morgan SA, Nadler DC, Yokoo R, et al. (2016) Biofuel metabolic engineering with biosensors. Current Opinion in Chemical Biology. 35: 150-158
Nadler DC, Morgan SA, Flamholz A, et al. (2016) Rapid construction of metabolite biosensors using domain-insertion profiling. Nature Communications. 7: 12266
Cassidy-Amstutz C, Oltrogge LM, Going CC, et al. (2016) Identification of a minimal peptide tag for in vivo and in vitro loading of encapsulin. Biochemistry
Oakes BL, Nadler DC, Flamholz A, et al. (2016) Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch. Nature Biotechnology. 34: 646-51
Chaijarasphong T, Nichols RJ, Kortright KE, et al. (2015) Programmed ribosomal frameshifting mediates expression of the α-carboxysome. Journal of Molecular Biology
Oakes BL, Nadler DC, Savage DF. (2014) Protein engineering of Cas9 for enhanced function Methods in Enzymology. 546: 491-511
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