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Katherine L.B. Borden, PhD

Affiliations: 
Dalhousie University, Halifax, Nova Scotia, Canada 
 Mount Sinai School of Medicine, New York, NY 
 Université de Montréal, Montréal, Canada 
Area:
molecular basis of cancer
Website:
https://www.iric.ca/en/research/principal-investigators/katherine-borden/
Google:
"Katherine L.B. Borden"
Bio:

https://www.iric.ca/en/research/principal-investigators/katherine-borden/?section=cv

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Publications

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Volpon L, Culjkovic-Kraljacic B, Osborne MJ, et al. (2016) Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. Proceedings of the National Academy of Sciences of the United States of America
Culjkovic B, Fernando T, Yang S, et al. (2013) The Eukaryotic Translation Initiation Factor 4E (eIF4E) Has Oncogenic Functions and May Represent a New Therapeutic Target In Diffuse Large B Cell Lymphoma (DLBCL) Blood. 122: 3785-3785
Volpon L, Osborne MJ, Capul AA, et al. (2010) Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E. Proceedings of the National Academy of Sciences of the United States of America. 107: 5441-6
Ploski JE, Topisirovic I, Park KW, et al. (2009) A mechanism of nucleocytoplasmic trafficking for the homeodomain protein PRH. Molecular and Cellular Biochemistry. 332: 173-81
Peng H, Gibson LC, Capili AD, et al. (2007) The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain. Journal of Molecular Biology. 370: 269-89
Djavani M, Topisirovic I, Zapata JC, et al. (2005) The proline-rich homeodomain (PRH/HEX) protein is down-regulated in liver during infection with lymphocytic choriomeningitis virus. Journal of Virology. 79: 2461-73
Topisirovic I, Kentsis A, Perez JM, et al. (2005) Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels. Molecular and Cellular Biology. 25: 1100-12
Topisirovic I, Guzman ML, McConnell MJ, et al. (2003) Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis. Molecular and Cellular Biology. 23: 8992-9002
Seker H, Rubbi C, Linke SP, et al. (2003) UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML. Oncogene. 22: 1620-8
Topisirovic I, Culjkovic B, Cohen N, et al. (2003) The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth. The Embo Journal. 22: 689-703
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