Bhavaani Jayaram, Ph.D.
|2011||Pharmaceutical Sciences||Wayne State University, Detroit, MI, United States|
Area:Pharmacy, Molecular Biology
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|Jayaram B, Kowluru A. (2012) Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 30: 1351-62|
|Syed I, Kyathanahalli CN, Jayaram B, et al. (2011) Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes. 60: 2843-52|
|Jayaram B, Syed I, Singh A, et al. (2011) Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells. Islets. 3: 48-57|
|Jayaram B, Syed I, Kyathanahalli CN, et al. (2011) Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets. Biochemical Pharmacology. 81: 1016-27|
|Kamath V, Kyathanahalli CN, Jayaram B, et al. (2010) Regulation of glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 299: E276-86|
|Syed I, Jayaram B, Subasinghe W, et al. (2010) Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells. Biochemical Pharmacology. 80: 874-83|