Gaurav Sahay, Ph.D.

Affiliations: 
2009 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Pharmacy
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Parents

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Alexander V. Kabanov grad student 2009 University of Nebraska Medical Center
 (Mechanism(s) of endocytosis for cellular entry of novel nanomaterials.)
Daniel G. Anderson post-doc MIT / Koch Institute
 (Post Doc)
Robert S. Langer post-doc MIT / Koch Institute
 (Post Doc)
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Publications

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Herrera-Barrera M, Gautam M, Lokras A, et al. (2023) Lipid Nanoparticle-Enabled Intracellular Delivery of Prime Editors. The Aaps Journal. 25: 65
Sun C, Seranova E, Cohen MA, et al. (2023) NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Reports. 42: 112372
Henderson MI, Eygeris Y, Jozic A, et al. (2022) Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles. Molecular Pharmaceutics
Herrera M, Kim J, Eygeris Y, et al. (2021) Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery. Biomaterials Science
Mukherjee A, MacDonald KD, Kim J, et al. (2020) Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models. Science Advances. 6
Kim J, Jozic A, Sahay G. (2020) Naturally Derived Membrane Lipids Impact Nanoparticle-Based Messenger RNA Delivery. Cellular and Molecular Bioengineering. 1-12
Patel S, Ashwanikumar N, Robinson E, et al. (2020) Author Correction: Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA. Nature Communications. 11: 3435
Eygeris Y, Patel S, Jozic A, et al. (2020) Deconvoluting Lipid Nanoparticle Structure for Messenger RNA Delivery. Nano Letters
Patel S, Ashwanikumar N, Robinson E, et al. (2020) Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA. Nature Communications. 11: 983
Rosch JG, Winter H, DuRoss AN, et al. (2019) Inverse-micelle synthesis of doxorubicin-loaded alginate/chitosan nanoparticles and assessment of breast cancer cytotoxicity. Colloid and Interface Science Communications. 28: 69-74
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