Donald Poirier

Affiliations: 
Universite Laval (Canada) 
Area:
Pharmaceutical Chemistry
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"Donald Poirier"
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Burguin A, Roy J, Ouellette G, et al. (2023) Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments. Journal of Clinical Medicine. 12
Poirier D, Roy J, Maltais R, et al. (2023) An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models. Cancers. 15
Maltais R, Sancéau JY, Poirier D, et al. (2023) A Concise, Gram-Scale Total Synthesis of Protectin DX and Related Labeled Versions via a Key Stereoselective Reduction of Enediyne. The Journal of Organic Chemistry
Poirier D. (2023) Description of Chemical Synthesis, Nuclear Magnetic Resonance Characterization and Biological Activity of Estrane-Based Inhibitors/Activators of Steroidogenesis. Molecules (Basel, Switzerland). 28
Ngueta AD, Roy J, Maltais R, et al. (2023) Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone. Molecules (Basel, Switzerland). 28
Poirier D, Maltais R, Rousseau JA, et al. (2022) Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution. Bioorganic Chemistry. 129: 106145
Poirier D, Nyachieo A, Romano A, et al. (2022) An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis model. The Journal of Steroid Biochemistry and Molecular Biology. 106136
Sancéau JY, Bélanger P, Maltais R, et al. (2022) An Improved Synthesis of Glucuronide Metabolites of Hindered Phenolic Xenoestrogens. Current Organic Synthesis
Maltais R, Roy J, Perreault M, et al. (2021) Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel. International Journal of Molecular Sciences. 22
Thériault JF, Poirier D, Lin SX. (2021) The multi-specific human 17 beta-hydroxysteroid dehydrogenase type 7: Non-competitive inhibitors can target different catalyses to facilitate breast cancer treatment. The Journal of Steroid Biochemistry and Molecular Biology. 105963
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