David W. Litchfield

The University of Western Ontario (Canada) 
Cell Biology, Biochemistry, Molecular Biology
"David Litchfield"
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Gyenis L, Menyhart D, Cruise ES, et al. (2022) Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics. Frontiers in Molecular Biosciences. 9: 909711
Strum SW, Gyenis L, Litchfield DW. (2021) CSNK2 in cancer: pathophysiology and translational applications. British Journal of Cancer
Roffey SE, Litchfield DW. (2021) CK2 Regulation: Perspectives in 2021. Biomedicines. 9
Wells CI, Drewry DH, Pickett JE, et al. (2021) Development of a potent and selective chemical probe for the pleiotropic kinase CK2. Cell Chemical Biology
Nouri-Nejad D, O'Donnell BL, Patil CS, et al. (2021) Pannexin 1 mutation found in melanoma tumour reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein. Molecular Biology of the Cell. mbcE19100585
Strum S, Gyenis L, Litchfield DW. (2020) CSNK2 in cancer: Pathophysiology and translational applications. Journal of Clinical Oncology. 38: e15594-e15594
Lefebvre C, Litchfield D, Allan A. (2019) Abstract 1282: Understanding the kinomic contributions to tyrosine kinase inhibitor resistance in triple negative breast cancer Cancer Research. 79: 1282-1282
Bowie LE, Maiuri T, Alpaugh M, et al. (2018) N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proceedings of the National Academy of Sciences of the United States of America
Kravic B, Harbauer AB, Romanello V, et al. (2017) In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy. Autophagy. 1-65
Münzer P, Walker-Allgaier B, Geue S, et al. (2017) CK2β critically regulates thrombopoiesis and Ca(2+)-triggered platelet activation in arterial thrombosis in vivo. Blood
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