Theresa A. Shapiro

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biochemistry, Molecular Biology
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"Theresa Shapiro"
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Publications

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Meyer KJ, Caton E, Shapiro TA. (2018) Model system identifies kinetic driver of Hsp90 inhibitor activity against African trypanosomes and . Antimicrobial Agents and Chemotherapy
Caton E, Nenortas E, Bakshi RP, et al. (2016) Hollow-Fiber Methodology for Pharmacokinetic/Pharmacodynamic Studies of Antimalarial Compounds. Current Protocols in Chemical Biology. 8: 29-58
Tang Girdwood SC, Nenortas E, Shapiro TA. (2015) Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons. Biochemical Pharmacology. 95: 227-37
Grab DJ, Nenortas E, Bakshi RP, et al. (2013) Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs. Parasitology International. 62: 461-3
Roy Chowdhury A, Bakshi R, Wang J, et al. (2010) The killing of African trypanosomes by ethidium bromide. Plos Pathogens. 6: e1001226
Woodard LE, Mott BT, Singhal V, et al. (2009) Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine. Pharmaceuticals (Basel, Switzerland). 2: 228-235
Moon DK, Singhal V, Kumar N, et al. (2009) Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice. Drug Development Research. 71: 76-81
Woodard LE, Chang W, Chen X, et al. (2009) Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose Journal of Medicinal Chemistry. 52: 7458-7462
Chen X, Xie S, Bhat S, et al. (2009) Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202
Rosenthal AS, Chen X, Liu JO, et al. (2009) Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203
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