Anna Marie Pyle

Affiliations: 
Yale University, Columbia University 
Area:
Ribozymes
Website:
http://www.pylelab.org/
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Children

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Rebecca L Adams grad student Yale (Cell Biology Tree)
Tanja Hann grad student Yale
Vi T. Chu grad student 2000 Columbia
Jennifer F. Swisher grad student 2000 Columbia
Phillip S. Pang grad student 2002 Columbia
Lin H. Su grad student 2002 Columbia
Jane M. Kawaoka grad student 2004 Columbia
Alexandre de Lencastre grad student 2005 Columbia
Stephanie Hamill grad student 2006 Columbia
Leven M. Wadley grad student 2006 Columbia
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Publications

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Li K, Zheng J, Wirawan M, et al. (2021) Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3). Nucleic Acids Research
Mao T, Israelow B, Lucas C, et al. (2021) A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice. Biorxiv : the Preprint Server For Biology
Jacobson ME, Becker KW, Palmer CR, et al. (2020) Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists. Acs Central Science. 6: 2008-2022
Manigrasso J, Chillón I, Genna V, et al. (2020) Visualizing group II intron dynamics between the first and second steps of splicing. Nature Communications. 11: 2837
Guo LT, Adams RL, Wan H, et al. (2020) Sequencing and structure probing of long RNAs using MarathonRT: a next-generation reverse transcriptase. Journal of Molecular Biology
Rawling DC, Jagdmann GE, Potapova O, et al. (2020) Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. Acs Chemical Biology. 15: 311-317
Ren X, Linehan MM, Iwasaki A, et al. (2019) RIG-I Recognition of RNA Targets: The Influence of Terminal Base Pair Sequence and Overhangs on Affinity and Signaling. Cell Reports. 29: 3807-3815.e3
Dickey TH, Song B, Pyle AM. (2019) RNA binding activates RIG-I by releasing an autorepressed signaling domain. Science Advances. 5: eaax3641
Jiang X, Muthusamy V, Fedorova O, et al. (2019) Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses. The Journal of Experimental Medicine
Van Zandt MC, Jagdmann GE, Whitehouse D, et al. (2019) Discovery of N-substituted 3-amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic acids as highly potent third generation inhibitors of human arginase I and II. Journal of Medicinal Chemistry
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