Greg Vilk, Ph.D.

Affiliations: 
2003 The University of Western Ontario (Canada) 
Area:
Cell Biology, Biochemistry, Molecular Biology
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"Greg Vilk"
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David W. Litchfield grad student 2003 The University of Western Ontario (Canada)
 (A functional study of the isozymes of protein kinase CK2 in mammalian cells with tetracycline-regulated expression of CK2.)
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Publications

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Turowec JP, Vilk G, Gabriel M, et al. (2013) Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α': implications for pathological roles of CK2 in promoting cancer cell survival. Oncotarget. 4: 560-71
Kriz J, Vilk G, Mazzuca DM, et al. (2012) A novel technique for the transplantation of pancreatic islets within a vascularized device into the greater omentum to achieve insulin independence. American Journal of Surgery. 203: 793-7
St-Denis NA, Bailey ML, Parker EL, et al. (2011) Localization of phosphorylated CK2alpha to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1. Journal of Cell Science. 124: 2341-8
Duncan JS, Turowec JP, Duncan KE, et al. (2011) A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling. Science Signaling. 4: ra30
Raaf J, Bischoff N, Klopffleisch K, et al. (2011) Interaction between CK2α and CK2β, the subunits of protein kinase CK2: thermodynamic contributions of key residues on the CK2α surface. Biochemistry. 50: 512-22
Turowec JP, Duncan JS, French AC, et al. (2010) Protein kinase CK2 is a constitutively active enzyme that promotes cell survival: strategies to identify CK2 substrates and manipulate its activity in mammalian cells. Methods in Enzymology. 484: 471-93
Duncan JS, Turowec JP, Vilk G, et al. (2010) Regulation of cell proliferation and survival: convergence of protein kinases and caspases. Biochimica Et Biophysica Acta. 1804: 505-10
Maher S, Vilk G, Kelleher F, et al. (2009) Chemical modification of the carboxyl terminal of nisin a with biotin does not abolish antimicrobial activity against the indicator organism, kocuria rhizophila International Journal of Peptide Research and Therapeutics. 15: 219-226
Vilk G, Weber JE, Turowec JP, et al. (2008) Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. Cellular Signalling. 20: 1942-51
Stolk M, Cooper E, Vilk G, et al. (2005) Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2. The Biochemical Journal. 386: 281-9
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