Greg Vilk, Ph.D.

2003 The University of Western Ontario (Canada) 
Cell Biology, Biochemistry, Molecular Biology
"Greg Vilk"
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David W. Litchfield grad student 2003 The University of Western Ontario (Canada)
 (A functional study of the isozymes of protein kinase CK2 in mammalian cells with tetracycline-regulated expression of CK2.)
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Turowec JP, Vilk G, Gabriel M, et al. (2013) Characterizing the convergence of protein kinase CK2 and caspase-3 reveals isoform-specific phosphorylation of caspase-3 by CK2α': implications for pathological roles of CK2 in promoting cancer cell survival. Oncotarget. 4: 560-71
St-Denis NA, Bailey ML, Parker EL, et al. (2011) Localization of phosphorylated CK2alpha to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1. Journal of Cell Science. 124: 2341-8
Duncan JS, Turowec JP, Duncan KE, et al. (2011) A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling. Science Signaling. 4: ra30
Raaf J, Bischoff N, Klopffleisch K, et al. (2011) Interaction between CK2α and CK2β, the subunits of protein kinase CK2: thermodynamic contributions of key residues on the CK2α surface. Biochemistry. 50: 512-22
Turowec JP, Duncan JS, French AC, et al. (2010) Protein kinase CK2 is a constitutively active enzyme that promotes cell survival: strategies to identify CK2 substrates and manipulate its activity in mammalian cells. Methods in Enzymology. 484: 471-93
Duncan JS, Turowec JP, Vilk G, et al. (2010) Regulation of cell proliferation and survival: convergence of protein kinases and caspases. Biochimica Et Biophysica Acta. 1804: 505-10
Vilk G, Weber JE, Turowec JP, et al. (2008) Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. Cellular Signalling. 20: 1942-51
Stolk M, Cooper E, Vilk G, et al. (2005) Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2. The Biochemical Journal. 386: 281-9
Donella-Deana A, Cesaro L, Sarno S, et al. (2003) Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity. The Biochemical Journal. 372: 841-9
Zhang C, Vilk G, Canton DA, et al. (2002) Phosphorylation regulates the stability of the regulatory CK2beta subunit. Oncogene. 21: 3754-64
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