Jeffrey M. Manthorpe, Ph.D.

2003 McGill University, Montreal, QC, Canada 
Organic Chemistry
"Jeffrey Manthorpe"
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Gordon L. Lange research assistant 1997-1998 University of Guelph (Canada)
James L. Gleason grad student 2003 McGill
 (A general method for the asymmetric synthesis of quaternary carbons: Reductive formation and alkylation of alpha,alpha-disubstituted enolates.)
Erick M. Carreira post-doc 2003-2006 ETH Zürich


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Monica Gill grad student 2008-2015 Carleton University
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Shields SWJ, Rosales CA, Roberts JA, et al. (2020) iTrEnDi: In Situ Trimethylation Enhancement Using Diazomethane: Improved and Expanded Glycerophospholipid and Sphingolipid Analyses via a Microscale Autonomous Derivatization Platform. Analytical Chemistry
Franklin ET, Shields SWJ, Manthorpe JM, et al. (2020) Coupling Headgroup and Alkene Specific Solution Modifications with Gas-Phase Ion/Ion Reactions for Sensitive Glycerophospholipid Identification and Characterization. Journal of the American Society For Mass Spectrometry. 31: 938-945
Gill MA, Manthorpe JM. (2019) Development of Palladium-Catalyzed Decarboxylative Allylation of Electron-Deficient Sulfones and Identification of Unusual Side Products. The Journal of Organic Chemistry
Shields S, Buist P, Manthorpe J. (2018) Asymmetric and Regiospecific Synthesis of Isotopically Labelled Cyclopropane Fatty Acid (9R,10S)-Dihydrosterculic Acid: Overcoming Spontaneous Protonation During Lithium-Sulfoxide Exchange­ Synopen. 2: 0168-0175
Betancourt SK, Canez CR, Shields SWJ, et al. (2017) Trimethylation Enhancement Using 13C Diazomethane (13C-TrEnDi): Gas-Phase Charge Inversion of Modified Phospholipid Cations for Enhanced Structural Characterization. Analytical Chemistry
Alenazi NA, Manthorpe JM, Lai EP. (2016) Selectivity Enhancement in Molecularly Imprinted Polymers for Binding of Bisphenol A. Sensors (Basel, Switzerland). 16
Canez CR, Shields SW, Bugno M, et al. (2016) Trimethylation enhancement using (13)C-diazomethane ((13)C-TrEnDi): Increased sensitivity and selectivity of phosphatidylethanolamine, phosphatidylcholine and phosphatidylserine lipids derived from complex biological samples. Analytical Chemistry
Alenazi NA, Manthorpe JM, Lai EPC. (2015) Selective extraction of BPA in milk analysis by capillary electrophoresis using a chemically modified molecularly imprinted polymer Food Control. 50: 778-783
Alenazi NA, Lai EP, Manthorpe JM. (2014) Enhanced selectivity of a molecularly imprinted polymer toward the target molecule via esterification of non-specific binding sites with diazomethane. Journal of Molecular Recognition : Jmr. 27: 755-62
Shields SW, Manthorpe JM. (2014) Efficient, scalable and economical preparation of tris(deuterium)- and 13C-labelled N-methyl-N-nitroso-p-toluenesulfonamide (Diazald®) and their conversion to labelled diazomethane. Journal of Labelled Compounds & Radiopharmaceuticals. 57: 674-9
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