John Barkinge, PhD
Affiliations: | Ben May Department for Cancer Biology and Institute for Genomics and Systems Bio | University of Chicago, Chicago, IL |
Area:
Systems analysis of proteinsGoogle:
"John Barkinge"Mean distance: 9.43 | S | N | B | C | P |
Parents
Sign in to add mentor| Kanteti Prasad | grad student | 2007 | University of Illinois, Chicago | |
| (The pro-apoptotic Siva-1 protein plays a significant role in DNA damage-induced programmed cell death) | ||||
| Richard Baker Jones | post-doc | 2008-2012 | Chicago | |
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Publications
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| Leung KK, Hause RJ, Barkinge JL, et al. (2014) Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome. Molecular & Cellular Proteomics : McP. 13: 1705-23 |
| Hause RJ, Leung KK, Barkinge JL, et al. (2012) Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors. Plos One. 7: e44471 |
| Wojcik J, Hantschel O, Grebien F, et al. (2010) A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain. Nature Structural & Molecular Biology. 17: 519-27 |
| Gudi R, Barkinge J, Hawkins S, et al. (2009) Siva-1 promotes K-48 polyubiquitination of TRAF2 and inhibits TCR-mediated activation of NF-kappaB. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 28: 25-38 |
| Barkinge JL, Gudi R, Sarah H, et al. (2009) The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis. Journal of Carcinogenesis. 8: 2 |
| Chuu CP, Chen RY, Barkinge JL, et al. (2008) Systems-level analysis of ErbB4 signaling in breast cancer: a laboratory to clinical perspective. Molecular Cancer Research : McR. 6: 885-91 |
| Gudi R, Barkinge J, Hawkins S, et al. (2006) Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD). Oncogene. 25: 3458-62 |
| Chu F, Barkinge J, Hawkins S, et al. (2005) Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2. Cancer Research. 65: 5301-9 |
| Chu F, Borthakur A, Sun X, et al. (2004) The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis. Apoptosis : An International Journal On Programmed Cell Death. 9: 83-95 |