Samuel K. Kulp, D.V.M., Ph.D.

Affiliations: 
2001 Veterinary Biosciences Ohio State University, Columbus, Columbus, OH 
 2002-2017 Medicinal Chemistry Ohio State University, Columbus, Columbus, OH 
 2018- Pharmaceutics and Pharmaceutical Chemistry Ohio State University, Columbus, Columbus, OH 
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"Samuel Kulp"
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Young C. Lin grad student 2001 Ohio State
 (Characterization of a larval tapeworm excretory -secretory product that inhibits steroidogenesis.)
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Publications

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Weng SC, Kashida Y, Kulp SK, et al. (2019) Retraction: Sensitizing Estrogen Receptor-negative Breast Cancer Cells to Tamoxifen with OSU-03012, a Novel Celecoxib-derived Phosphoinositide-dependent Protein Kinase-1/Akt Signaling Inhibitor. Molecular Cancer Therapeutics. 18: 869
Cheng H, Xie Z, Jones WP, et al. (2016) Preclinical Pharmacokinetics Study of R- and S-Enantiomers of the Histone Deacetylase Inhibitor, AR-42 (NSC 731438), in Rodents. The Aaps Journal
Hsu EC, Kulp SK, Huang HL, et al. (2016) Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer. Carcinogenesis
Chao MW, Chu PC, Chuang HC, et al. (2015) Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability. Oncotarget
Tseng YC, Kulp SK, Lai IL, et al. (2015) Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia. Journal of the National Cancer Institute. 107
Dokla EM, Fang CS, Lai PT, et al. (2015) Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators. Chemmedchem
Hsu EC, Kulp SK, Huang HL, et al. (2015) Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae. Neoplasia (New York, N.Y.). 17: 497-508
Yan R, Chuang HC, Kapuriya N, et al. (2015) Exploitation of the ability of γ-tocopherol to facilitate membrane co-localization of Akt and PHLPP1 to develop PHLPP1-targeted Akt inhibitors. Journal of Medicinal Chemistry. 58: 2290-8
Chou CC, Lee KH, Lai IL, et al. (2014) AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis. Cancer Research. 74: 4783-95
Lai IL, Chou CC, Lai PT, et al. (2014) Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells. Carcinogenesis. 35: 2203-13
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