Ishwar Radhakrishnan
Affiliations: | Interdepartmental Biological Sciences Program | Northwestern University, Evanston, IL |
Area:
General BiophysicsWebsite:
https://www.molbiosci.northwestern.edu/people/core-faculty/ishwar-radhakrishnan.htmlGoogle:
"Ishwar Radhakrishnan"Bio:
https://books.google.com/books?id=2p8vAQAAIAAJ
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Parents
Sign in to add mentorDinshaw J. Patel | grad student | 1994 | Columbia (Chemistry Tree) | |
(Structural investigations of triple-stranded DNA by nuclear magnetic resonance spectroscopic techniques in aqueous solution.) |
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Publications
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Patel AB, He Y, Radhakrishnan I. (2023) Histone acetylation and deacetylation - Mechanistic insights from structural biology. Gene. 890: 147798 |
Patel AB, Qing J, Tam KH, et al. (2023) Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex. Nature Communications. 14: 3061 |
Marcum RD, Hsieh J, Giljen M, et al. (2021) A Capped Tudor Domain within a Core Subunit of the Sin3L/Rpd3L Histone Deacetylase Complex Binds to Nucleic Acid G-Quadruplexes. The Journal of Biological Chemistry. 101558 |
Marcum RD, Radhakrishnan I. (2020) The neuronal transcription factor Myt1L interacts via a conserved motif with the PAH1 domain of Sin3 to recruit the Sin3L/Rpd3L histone deacetylase complex. Febs Letters |
Marcum RD, Radhakrishnan I. (2019) Inositol phosphates and core subunits of the Sin3L/Rpd3L histone deacetylase (HDAC) complex up-regulate deacetylase activity. The Journal of Biological Chemistry |
Daffern N, Chen Z, Zhang Y, et al. (2018) Solution NMR Studies of the Ligand-Binding Domain of an Orphan Nuclear Receptor Reveals a Dynamic Helix in the Ligand-Binding Pocket. Biochemistry |
Clark MD, Zhang Y, Radhakrishnan I. (2015) Solution NMR Studies of an Alternative Mode of Sin3 Engagement by the Sds3 Subunit in the Histone Deacetylase-Associated Sin3L/Rpd3L Corepressor Complex. Journal of Molecular Biology |
Clark M, Kumar GS, Marcum R, et al. (2015) Molecular Basis for the Mechanism of Constitutive CBP/p300 Coactivator Recruitment by CRTC1-MAML2 and its Implications in cAMP Signaling. Biochemistry |
Clark MD, Marcum R, Graveline R, et al. (2015) Structural insights into the assembly of the histone deacetylase-associated Sin3L/Rpd3L corepressor complex. Proceedings of the National Academy of Sciences of the United States of America |
Xie T, Zmyslowski AM, Zhang Y, et al. (2015) Structural Basis for Multi-specificity of MRG Domains. Structure (London, England : 1993). 23: 1049-57 |