Johnathan C. Maher, Ph.D.
Affiliations: | 2006 | University of Miami, Coral Gables, FL |
Area:
Cell Biology, OncologyGoogle:
"Johnathan Maher"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Theodore J. Lampidis | grad student | 2006 | University of Miami | |
| (Treatment of tumor cells with the glycolytic inhibitor, 2-deoxy-D-glucose: Effects and mechanisms of resistance.) | ||||
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| Wangpaichitr M, Wu C, You M, et al. (2009) N',N'-Dimethyl-N',N'-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS). Cancers. 1: 23-38 |
| Wangpaichitr M, Savaraj N, Maher J, et al. (2008) Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines. Molecular Cancer Therapeutics. 7: 1506-13 |
| Kurtoglu M, Gao N, Shang J, et al. (2007) Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation. Molecular Cancer Therapeutics. 6: 3049-58 |
| Kurtoglu M, Maher JC, Lampidis TJ. (2007) Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells. Antioxidants & Redox Signaling. 9: 1383-90 |
| Maher JC, Wangpaichitr M, Savaraj N, et al. (2007) Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose. Molecular Cancer Therapeutics. 6: 732-41 |
| Lampidis TJ, Kurtoglu M, Maher JC, et al. (2006) Efficacy of 2-halogen substituted D-glucose analogs in blocking glycolysis and killing "hypoxic tumor cells". Cancer Chemotherapy and Pharmacology. 58: 725-34 |
| Maher JC, Savaraj N, Priebe W, et al. (2005) Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression. Pancreas. 30: e34-9 |
| Maher JC, Krishan A, Lampidis TJ. (2004) Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Cancer Chemotherapy and Pharmacology. 53: 116-22 |