Everett M. Stone, Ph.D.
Affiliations: | 2006 | ICMB | University of Texas at Austin, Austin, Texas, U.S.A. |
Area:
Biochemistry, Molecular BiologyGoogle:
"Everett Stone"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Walter Fast | grad student | 2006 | UT Austin | |
| (The catalytic mechanism of dimethylarginine dimethylaminohydrolase (DDAH) from Pseudomonas aeruginosa.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Blazeck J, Karamitros CS, Ford K, et al. (2022) Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme. Nature Catalysis. 5: 952-967 |
| Karamitros CS, Murray K, Winemiller B, et al. (2022) Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118979119 |
| Karamitros CS, Murray K, Sugiyama Y, et al. (2020) Conformational Dynamics Contribute to Substrate Selectivity and Catalysis in Human Kynureninase. Acs Chemical Biology |
| Lu WC, Saha A, Yan W, et al. (2020) Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proceedings of the National Academy of Sciences of the United States of America |
| Badgley MA, Kremer DM, Maurer HC, et al. (2020) Cysteine depletion induces pancreatic tumor ferroptosis in mice. Science (New York, N.Y.). 368: 85-89 |
| Cao JY, Poddar A, Magtanong L, et al. (2019) A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity. Cell Reports. 26: 1544-1556.e8 |
| Coma S, Cavanaugh J, Nolan J, et al. (2019) Abstract B008: Treatment of IDO1 and TDO2 positive tumors with a kynurenine-degrading enzyme: A highly differentiated approach from IDO1 inhibition Cancer Immunology Research. 7 |
| Wilder CS, Saha A, Georgiou G, et al. (2019) Abstract 2996: Systemic depletion of L-methionine with an engineered human enzyme for the treatment of melanoma Cancer Research |
| Gjuka D, Georgiou G, Stone EM. (2019) Abstract LB-A18: The frequent tumor deletion of MTAP is a newly recognized potent immune checkpoint that is effectively reversed by a human methylthioadenosine degrading drug candidate Molecular Cancer Therapeutics. 18 |
| Triplett TA, Garrison KC, Marshall N, et al. (2018) Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme. Nature Biotechnology |