Jason Moffat, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Molecular Biology, Cell Biology
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"Jason Moffat"
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Brenda Andrews grad student 2002 University of Toronto
 (Functions for Pho85 cyclin -dependent protein kinases in Saccharomyces cerevisiae.)
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Publications

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Amitzi L, Cozma E, Tong AHY, et al. (2024) Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency. G3 (Bethesda, Md.)
Lin P, Lourenco C, Cruickshank J, et al. (2023) Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality. Cancer Research. OF1-OF15
Varland S, Silva RD, Kjosås I, et al. (2023) N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity. Nature Communications. 14: 6774
Billmann M, Ward HN, Aregger M, et al. (2023) Reproducibility metrics for context-specific CRISPR screens. Cell Systems. 14: 418-422.e2
Bock C, Datlinger P, Chardon F, et al. (2022) High-content CRISPR screening. Nature Reviews. Methods Primers. 2
Chan K, Farias AG, Lee H, et al. (2022) Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors. Heliyon. e12744
Masud SN, Chandrashekhar M, Aregger M, et al. (2022) Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux. Nature Chemical Biology
Masud SN, Chandrashekhar M, Aregger M, et al. (2022) Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux. Nature Chemical Biology
Mair B, Aregger M, Tong AHY, et al. (2022) A Method to Map Gene Essentiality of Human Pluripotent Stem Cells by Genome-Scale CRISPR Screens with Inducible Cas9. Methods in Molecular Biology (Clifton, N.J.). 2377: 1-27
Rahman M, Billmann M, Costanzo M, et al. (2021) A method for benchmarking genetic screens reveals a predominant mitochondrial bias. Molecular Systems Biology. 17: e10013
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