Jason Moffat, Ph.D.

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Genetics, Molecular Biology, Cell Biology
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"Jason Moffat"
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Brenda Andrews grad student 2002 University of Toronto
 (Functions for Pho85 cyclin -dependent protein kinases in Saccharomyces cerevisiae.)
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Publications

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Bailey ML, Tieu D, Habsid A, et al. (2021) Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene . Life Science Alliance. 4
Serra SA, Stojakovic P, Amat R, et al. (2021) LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions. Proceedings of the National Academy of Sciences of the United States of America. 118
Rahman M, Billmann M, Costanzo M, et al. (2021) A method for benchmarking genetic screens reveals a predominant mitochondrial bias. Molecular Systems Biology. 17: e10013
Jain P, Dvorkin-Gheva A, Mollen E, et al. (2021) NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4. Science Advances. 7
Rehman SK, Haynes J, Collignon E, et al. (2021) Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy. Cell. 184: 226-242.e21
Lamanna J, Scott EY, Edwards HS, et al. (2020) Digital microfluidic isolation of single cells for -Omics. Nature Communications. 11: 5632
Lawson KA, Sousa CM, Zhang X, et al. (2020) Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Nature
Aregger M, Lawson KA, Billmann M, et al. (2020) Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. Nature Metabolism. 2: 499-513
Aubry A, Pearson JD, Huang K, et al. (2020) Functional genomics identifies new synergistic therapies for retinoblastoma. Oncogene
Vora P, Venugopal C, Salim SK, et al. (2020) The Rational Development of CD133-Targeting Immunotherapies for Glioblastoma. Cell Stem Cell
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