Robert Warner Chambers

Biochemistry and Molecular Biology Dalhousie University, Halifax, Nova Scotia, Canada 
nucleotide chemistry, molecular mechanisms of mutation
"Robert Chambers"

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Frederick H. Carpenter grad student 1954 UC Berkeley
 (Ammonolysis of peptides : a method of determining C-terminal amino acids)
H. Gobind Khorana post-doc 1956 UBC
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Chambers RW. (1993) Site-directed mutagenesis in single cells: transitions produced by DNA carrying a single O6-alkylguanine residue. Mutation Research. 299: 123-33
Chambers RW. (1991) Site-specific mutagenesis in cells with normal DNA repair systems: transitions produced from DNA carrying a single O6-alkylguanine. Nucleic Acids Research. 19: 2485-8
Borowy-Borowski H, Chambers RW. (1989) Solid-phase synthesis and side reactions of oligonucleotides containing O-alkylthymine residues. Biochemistry. 28: 1471-7
Chambers RW. (1989) On the nature of suppression by Escherichia coli HF4714. Mutation Research. 210: 207-9
Chambers RW, Sledziewska-Gojska E, Hirani-Hojatti S. (1988) In vivo effect of DNA repair on the transition frequency produced from a single O6-methyl- or O6-n-butyl-guanine in a T:G base pair. Molecular & General Genetics : Mgg. 213: 325-31
Stuart GR, Chambers RW. (1987) Synthesis and properties of oligodeoxynucleotides with an AP site at a preselected position. Nucleic Acids Research. 15: 7451-62
Borowy-Borowski H, Chambers RW. (1987) A study of side reactions occurring during synthesis of oligodeoxynucleotides containing O6-alkyldeoxyguanosine residues at preselected sites. Biochemistry. 26: 2465-71
Chambers RW. (1985) Chemical carcinogenesis: a biochemical overview. Clinical Biochemistry. 18: 158-68
Chambers RW, Sledziewska-Gojska E, Hirani-Hojatti S, et al. (1985) uvrA and recA mutations inhibit a site-specific transition produced by a single O6-methylguanine in gene G of bacteriophage phi X174. Proceedings of the National Academy of Sciences of the United States of America. 82: 7173-7
Jericevi? Z, Ku?an I, Chambers RW. (1982) Photochemical cleavage of phosphodiester bonds in oligoribonucleotides. Biochemistry. 21: 6563-7
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