Paul B. Sigler
Affiliations: | Yale University, New Haven, CT |
Area:
regulation of gene expression mediated by proteins that bind specifically to DNA, signal transduction pathway involved in vision, structural biologyWebsite:
http://www.csb.yale.edu/people/sigler/index.htmlGoogle:
"Paul B. Sigler"Bio:
(1934 - 2000)
http://www.nasonline.org/member-directory/deceased-members/43385.html
http://news.yale.edu/2000/01/13/noted-yale-structural-biologist-paul-sigler-dies
http://rna.berkeley.edu/Publications/tbs-25-221.pdf
Mean distance: 8.32 | S | N | B | C | P |
Children
Sign in to add trainee| Jonathan Hancock Dennis | research assistant | 1994-1997 | Yale |
| Youxing Jiang | grad student | (Computational Biology Tree) | |
| Zhaohui Xu | grad student | (Neurotree) | |
| Catherine L Lawson | grad student | 1982-1987 | Chicago (StructuralBiologyTree) |
| Ronen Marmorstein | grad student | 1989 | Chicago |
| Kathryn M. Ferguson | grad student | 1996 | Yale |
| Rachelle Gaudet | grad student | 1993-1998 | Yale |
| Benjamin A. Berkowitz | grad student | 2001 | Yale |
| Charu Chaudhry | grad student | 2003 | Yale |
| Joel A. Hirsch | post-doc | Yale (Crystallography Tree) | |
| Ben Luisi | post-doc | ||
| Joseph P. Noel | post-doc | 1993 | Yale |
| Gourisankar Ghosh | post-doc | 1995 | Yale |
| Fraydoon Rastinejad | post-doc | 1992-1995 | Yale |
| James H. Geiger | post-doc | 1991-1996 | Yale |
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Publications
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| Slep KC, Kercher MA, Wieland T, et al. (2008) Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proceedings of the National Academy of Sciences of the United States of America. 105: 6243-8 |
| Lee S, Sowa ME, Watanabe YH, et al. (2003) The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell. 115: 229-40 |
| Chaudhry C, Farr GW, Todd MJ, et al. (2003) Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics. The Embo Journal. 22: 4877-87 |
| Juo ZS, Kassavetis GA, Wang J, et al. (2003) Crystal structure of a transcription factor IIIB core interface ternary complex. Nature. 422: 534-9 |
| Berkowitz B, Huang DB, Chen-Park FE, et al. (2002) The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. The Journal of Biological Chemistry. 277: 24694-700 |
| Korkhin Y, Littlefield O, Nelson PJ, et al. (2001) Preparation of components of archaeal transcription preinitiation complex. Methods in Enzymology. 334: 227-39 |
| Slep KC, Kercher MA, He W, et al. (2001) Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A. Nature. 409: 1071-7 |
| Ma J, Sigler PB, Xu Z, et al. (2000) A dynamic model for the allosteric mechanism of GroEL. Journal of Molecular Biology. 302: 303-13 |
| Tsai FT, Sigler PB. (2000) Structural basis of preinitiation complex assembly on human pol II promoters. The Embo Journal. 19: 25-36 |
| Chen L, Sigler PB. (1999) The crystal structure of a GroEL/peptide complex: plasticity as a basis for substrate diversity. Cell. 99: 757-68 |