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William S. Allison

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
bioenergetics; molecular mechanism of ATP synthase
Website:
http://www-chem.ucsd.edu/faculty/profiles/allison_william_s.html
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"William Allison"
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Parents

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Nathan O. Kaplan grad student 1963 Brandeis
 (The comparative enzymology of triosephosphate dehydrogenase)
J. Ieuan Harris post-doc 1966 MRC-LMB
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Publications

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Ren H, Bandyopadhyay S, Allison WS. (2006) The alpha3(betaMet222Ser/Tyr345Trp)3gamma subcomplex of the TF1-ATPase does not hydolyze ATP at a significant rate until the substrate binds to the catalytic site of the lowest affinity. Biochemistry. 45: 6222-30
Bandyopadhyay S, Muneyuki E, Allison WS. (2005) The characteristics of the (alpha V371C)3(beta R337C)3 gamma double mutant subcomplex of the TF1-ATPase indicate that the catalytic site at the alpha TP-beta TP interface with bound MgADP in crystal structures of MF1 represents a catalytic site containing inhibitory MgADP. Biochemistry. 44: 2441-8
Bandyopadhyay S, Allison WS. (2004) GammaM23K, gammaM232K, and gammaL77K single substitutions in the TF1-ATPase lower ATPase activity by disrupting a cluster of hydrophobic side chains. Biochemistry. 43: 9495-501
Bandyopadhyay S, Allison WS. (2004) The ionic track in the F1-ATPase from the thermophilic Bacillus PS3. Biochemistry. 43: 2533-40
Bandyopadhyay S, Valder CR, Huynh HG, et al. (2002) The beta G156C substitution in the F1-ATPase from the thermophilic Bacillus PS3 affects catalytic site cooperativity by destabilizing the closed conformation of the catalytic site. Biochemistry. 41: 14421-9
Malyan AN, Allison WS. (2002) Properties of noncatalytic sites of thioredoxin-activated chloroplast coupling factor 1 Biochimica Et Biophysica Acta - Bioenergetics. 1554: 153-158
Bandyopadhyay S, Ren H, Wang CS, et al. (2002) The (alpha F(357)C)(3)(beta R(372)C)(3)gamma subcomplex of the F(1)-ATPase from the thermophilic Bacillus PS3 has altered ATPase activity after cross-linking alpha and beta subunits at noncatalytic site interfaces. Biochemistry. 41: 3226-34
Dong K, Ren H, Allison WS. (2002) The fluorescence spectrum of the introduced tryptophans in the alpha 3(beta F155W)3gamma subcomplex of the F1-ATPase from the thermophilic Bacillus PS3 cannot be used to distinguish between the number of nucleoside di- and triphosphates bound to catalytic sites. The Journal of Biological Chemistry. 277: 9540-7
Allison WS, Ren H, Dou C. (2000) Inhibitory Mg-ADP-fluoroaluminate complexes bound to catalytic sites of F(1)-ATPases: are they ground-state or transition-state analogs? Journal of Bioenergetics and Biomembranes. 32: 531-8
Ren H, Allison WS. (2000) On what makes the gamma subunit spin during ATP hydrolysis by F(1). Biochimica Et Biophysica Acta. 1458: 221-33
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