Irina Chernyakov, Ph.D.

Affiliations: 
2008 University of Rochester, Rochester, NY 
Area:
Biochemistry, Molecular Biology
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"Irina Chernyakov"
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Elizabeth J. Grayhack grad student 2008 Rochester
 (Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22, and the 5'-3' exonucleases Rat1 and Xrn1.)
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Publications

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Chernyakov I, Santiago-Tirado F, Bretscher A. (2013) Active segregation of yeast mitochondria by Myo2 is essential and mediated by Mmr1 and Ypt11 Current Biology. 23: 1818-1824
Dewe JM, Whipple JM, Chernyakov I, et al. (2012) The yeast rapid tRNA decay pathway competes with elongation factor 1A for substrate tRNAs and acts on tRNAs lacking one or more of several modifications. Rna (New York, N.Y.). 18: 1886-96
Whipple JM, Lane EA, Chernyakov I, et al. (2011) The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA. Genes & Development. 25: 1173-84
Chernyakov I, Baker MA, Grayhack EJ, et al. (2008) Chapter 11. Identification and analysis of tRNAs that are degraded in Saccharomyces cerevisiae due to lack of modifications. Methods in Enzymology. 449: 221-37
Chernyakov I, Whipple JM, Kotelawala L, et al. (2008) Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1. Genes & Development. 22: 1369-80
Alexandrov A, Chernyakov I, Gu W, et al. (2006) Rapid tRNA decay can result from lack of nonessential modifications. Molecular Cell. 21: 87-96
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