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Gilbert J. Mannering

Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
drug metabolism, biochemical toxicology
"Gilbert Mannering"

(1917 - 2004)

Gilbert Mannering, Professor of Pharmacology at the University of Minnesota from 1962 to 1987, died of natural causes, March 20, 2004. A man of seemingly endless energy (he toured the Amazon basin at the age of 83!) and an unbridled zest for life, he was one of the fortunate few who enjoyed an extraordinarily hardy constitution and was rarely, if ever, ill until late in life when he was diagnosed with type 2 diabetes, and very late in life when he endured vascular dementia. Professor Mannering had been a regular/emeritus member of the American Society of Pharmacology and Experimental Therapeutics since 1956. A memorial service celebrating his life was held on April 3, 2004, at the University Club (his favorite local haunt), St. Paul, Minnesota.
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Mean distance: 16.53 (cluster 6)
Cross-listing: Neurotree


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Conrad (Arnold) Elvehjem grad student 1944 UW Madison
 (Newer dietary essentials required by the guinea pig)


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Akira E. Takemori grad student 1958 UW Madison (Neurotree)
Thomas R. Tephly grad student 1962 UW Madison
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Mannering GJ. (2001) A life in science: biochemist-nutritionist-forensic toxicologist-pharmacologist. Drug Metabolism Reviews. 33: 81-116
Mannering GJ, Shoeman JA. (1996) Murine cytochrome P4503A is induced by 2-methyl-3-buten-2-ol, 3-methyl-1-pentyn-3-ol(meparfynol), and tert-amyl alcohol. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 26: 487-93
Mannering GJ, Shoeman JA, Shoeman DW. (1994) Effects of colupulone, a component of hops and brewers yeast, and chromium on glucose tolerance and hepatic cytochrome P450 in nondiabetic and spontaneously diabetic mice. Biochemical and Biophysical Research Communications. 200: 1455-62
Mannering GJ, Shoeman JA. (1994) Induction of murine cytochrome P4503A by the lichen constituents usnic and vulpinic acids. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 22: 663-5
Iba MM, Gander JE, Mannering GJ. (1993) Lipid peroxidation-cytochrome P450 interactions. Use of linoleic acid hydroperoxide in the characterization of the spin-state of membrane-bound P450. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 23: 227-39
Deloria LB, Mannering GJ. (1993) Interferon induces sleep and other CNS responses in mice recovering from hexobarbital anesthesia. Neuropharmacology. 32: 1433-6
Kuwahara SK, Mannering GJ. (1993) Effects of interferon, polyriboinosinic acid--polyribocytidilic acid and steroids on the cytochrome P450 system of cultured primary mouse hepatocytes. Pharmacology & Toxicology. 72: 199-204
Mannering GJ, Shoeman JA, Deloria LB. (1992) Identification of the antibiotic hops component, colupulone, as an inducer of hepatic cytochrome P-4503A in the mouse. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 20: 142-7
Gooderham NJ, Mannering GJ. (1990) In vitro translational activity of messenger-RNA isolated from mice treated with the interferon inducer, polyriboinosinic acid.polyribocytidylic acid. Biochemical Pharmacology. 39: 865-71
Mannering GJ, Deloria LB, Abbott V. (1988) Role of xanthine oxidase in the interferon-mediated depression of the hepatic cytochrome P-450 system in mice. Cancer Research. 48: 2107-12
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