Aneel K. Aggarwal

Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Protein-nucleic acid interactions: studied by X-ray crystallography and other biophysical methods
"Aneel Aggarwal"
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Rechkoblit O, Choudhury JR, Buku A, et al. (2018) Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine. Scientific Reports. 8: 12702
Jain R, Choudhury JR, Buku A, et al. (2017) Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-ι. Scientific Reports. 7: 43904
Rechkoblit O, Gupta YK, Malik R, et al. (2016) Structure and mechanism of human PrimPol, a DNA polymerase with primase activity. Science Advances. 2: e1601317
Jain R, Coloma J, García-Sastre A, et al. (2016) Structure of the NS3 helicase from Zika virus. Nature Structural & Molecular Biology
Callahan SJ, Luyten YA, Gupta YK, et al. (2016) Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities. Plos Biology. 14: e1002442
Coloma J, Johnson RE, Prakash L, et al. (2016) Human DNA polymerase α in binary complex with a DNA:DNA template-primer. Scientific Reports. 6: 23784
Gupta YK, Chan SH, Xu SY, et al. (2015) Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I. Nature Communications. 6: 7363
Jain R, Rajashankar KR, Buku A, et al. (2014) Crystal structure of yeast DNA polymerase ε catalytic domain. Plos One. 9: e94835
Jain R, Vanamee ES, Dzikovski BG, et al. (2014) An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε. Journal of Molecular Biology. 426: 301-8
Liu W, Ma Q, Wong K, et al. (2013) Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release. Cell. 155: 1581-95
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