Pratiq Patel
Affiliations: | Chemistry | Ohio State University, Columbus, Columbus, OH |
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| Woodard JL, Huntsman AC, Patel PA, et al. (2018) Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones. Bioorganic & Medicinal Chemistry |
| Patel PA, Kvaratskhelia N, Mansour Y, et al. (2016) Indole-based allosteric inhibitors of HIV-1 integrase. Bioorganic & Medicinal Chemistry Letters |
| Slaughter A, Jurado KA, Deng N, et al. (2014) The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase. Retrovirology. 11: 100 |
| Feng L, Sharma A, Slaughter A, et al. (2013) The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors. The Journal of Biological Chemistry. 288: 15813-20 |
| Jurado KA, Wang H, Slaughter A, et al. (2013) Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation. Proceedings of the National Academy of Sciences of the United States of America. 110: 8690-5 |
| Wang H, Jurado KA, Wu X, et al. (2012) HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Research. 40: 11518-30 |