Celia A. Schiffer

1997- Biochemistry & Molecular Biotechnology University of Massachusetts Chan Medical School 
Structural basis for molecular recognition in HIV Protease
"celia schiffer"
Mean distance: 8.63


Sign in to add mentor
Robert M. Stroud grad student 1986-1992 UCSF
 (Protein structure determination)
Wilfred F. van Gunsteren post-doc 1992-1994 ETH Zürich
Anthony A. Kossiakoff post-doc 1994-1997 Genentech, Inc.
BETA: Related publications


You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Flynn JM, Huang QYJ, Zvornicanin SN, et al. (2023) Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease. Acs Infectious Diseases
Lockbaum GJ, Rusere LN, Henes M, et al. (2023) HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues. European Journal of Medicinal Chemistry. 257: 115501
Spielvogel E, Lee SK, Zhou S, et al. (2023) Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance. Elife. 12
Shaqra AM, Zvornicanin SN, Huang QYJ, et al. (2022) Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance. Nature Communications. 13: 3556
Zephyr J, Nageswara Rao D, Vo SV, et al. (2022) Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance. Journal of Molecular Biology. 167503
Zephyr J, Kurt Yilmaz N, Schiffer CA. (2021) Viral proteases: Structure, mechanism and inhibition. The Enzymes. 50: 301-333
Leidner F, Kurt Yilmaz N, Schiffer CA. (2021) Deciphering Complex Mechanisms of Resistance and Loss of Potency through Coupled Molecular Dynamics and Machine Learning. Journal of Chemical Theory and Computation
Rusere LN, Lockbaum GJ, Henes M, et al. (2020) Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere. Journal of Medicinal Chemistry
Matthew AN, Zephyr J, Nageswara Rao D, et al. (2020) Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors. Mbio. 11
Schiffer C. (2020) Constraining evolution → avoiding drug resistance: lessons from viruses The Faseb Journal. 34: 1-1
See more...