Robert B. Rose

Molecular and Structural Biochemistry North Carolina State University, Raleigh, NC 
Transcriptional regulation of cell specificity, Etiology of diseases associated with mis-regulation of transcription, particularly diabetes, Protein X-ray crystallography and small angle scattering, Evolution of protein structure
"Robert Rose"
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Robert M. Stroud grad student 1989-1996 UCSF
 (Structure of HIV-1 and SIV proteases wih implications for the catalytic mechanism and drug resistance)
Thomas C. Alber post-doc 1996-2001 UC Berkeley


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Cheng Wan grad student 2008 NCSU
Helen Y. Rho grad student 2010 NCSU
Dongli Wang grad student 2012 NCSU
Xun Lu grad student 2013 NCSU
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Buhrman G, Enríquez P, Dillard L, et al. (2021) Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from 2-Oxoglutarate Carboxylase. Biochemistry
Somalinga V, Buhrman G, Arun A, et al. (2016) A High-Resolution Crystal Structure of a Psychrohalophilic α-Carbonic Anhydrase from Photobacterium profundum Reveals a Unique Dimer Interface. Plos One. 11: e0168022
Lu H, Yuan W, Cheng J, et al. (2016) Modeling the Growth of Archaeon Halobacterium halobium Affected by Temperature and Light. Applied Biochemistry and Biotechnology
Friedenberg SG, Buhrman G, Chdid L, et al. (2015) Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs. Immunogenetics
Wang D, Coco MW, Rose RB. (2015) Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated. The Journal of Biological Chemistry. 290: 4319-29
Golla JP, Zhao J, Mann IK, et al. (2014) Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold. Biochemical and Biophysical Research Communications. 449: 248-55
Babin V, Wang D, Rose RB, et al. (2013) Binding polymorphism in the DNA bound state of the Pdx1 homeodomain. Plos Computational Biology. 9: e1003160
Lu X, Guanga GP, Wan C, et al. (2012) A novel DNA binding mechanism for maf basic region-leucine zipper factors inferred from a MafA-DNA complex structure and binding specificities. Biochemistry. 51: 9706-17
Rho H, Jones CN, Rose RB. (2010) Kinetic stability may determine the interaction dynamics of the bifunctional protein DCoH1, the dimerization cofactor of the transcription factor HNF-1α . Biochemistry. 49: 10187-97
Martin SL, Guenther RH, Sit TL, et al. (2010) Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1458-62
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