Robert B. Rose

Affiliations:

Molecular and Structural Biochemistry

North Carolina State University, Raleigh, NC

Area:

Transcriptional regulation of cell specificity, Etiology of diseases associated with mis-regulation of transcription, particularly diabetes, Protein X-ray crystallography and small angle scattering, Evolution of protein structure

Parents

Robert M. Stroud	grad student	1989-1996	UCSF
(Structure of HIV-1 and SIV proteases wih implications for the catalytic mechanism and drug resistance)
Thomas C. Alber	post-doc	1996-2001	UC Berkeley

Children

Cheng Wan	grad student	2008	NCSU
Helen Y. Rho	grad student	2010	NCSU
Dongli Wang	grad student	2012	NCSU
Xun Lu	grad student	2013	NCSU

Collaborators

BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.
Enríquez P, Krajewski K, Strahl BD, et al. (2021) Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone H3K14. The Journal of Biological Chemistry. 101145
Khund-Sayeed S, He X, Holzberg T, et al. (2016) 5-Hydroxymethylcytosine in E-box motifs ACAT\|GTG and ACAC\|GTG increases DNA-binding of the B-HLH transcription factor TCF4. Integrative Biology : Quantitative Biosciences From Nano to Macro
Wang D, Coco MW, Rose RB. (2015) Interactions with the bifunctional interface of the transcriptional coactivator DCoH1 are kinetically regulated. The Journal of Biological Chemistry. 290: 4319-29
Golla JP, Zhao J, Mann IK, et al. (2014) Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG\|GTG) increases binding of the Tcf3\|Ascl1 helix-loop-helix heterodimer 10-fold. Biochemical and Biophysical Research Communications. 449: 248-55
Babin V, Wang D, Rose RB, et al. (2013) Binding polymorphism in the DNA bound state of the Pdx1 homeodomain. Plos Computational Biology. 9: e1003160
Lu X, Guanga GP, Wan C, et al. (2012) A novel DNA binding mechanism for maf basic region-leucine zipper factors inferred from a MafA-DNA complex structure and binding specificities. Biochemistry. 51: 9706-17
Rho H, Jones CN, Rose RB. (2010) Kinetic stability may determine the interaction dynamics of the bifunctional protein DCoH1, the dimerization cofactor of the transcription factor HNF-1α . Biochemistry. 49: 10187-97
Longo A, Guanga GP, Rose RB. (2007) Structural basis for induced fit mechanisms in DNA recognition by the Pdx1 homeodomain. Biochemistry. 46: 2948-57
Wan C, Tempel W, Liu ZJ, et al. (2005) Structure of the conserved transcriptional repressor enhancer of rudimentary homolog. Biochemistry. 44: 5017-23
Rose RB, Pullen KE, Bayle JH, et al. (2004) Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2. Biochemistry. 43: 7345-55