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David Bruce McKay

Stanford University Medical Center, Palo Alto, CA, United States 
crystallographic structure determination and biophysical studies of proteins and RNA
"David McKay"
Mean distance: 7.83


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Clyde Allen Hutchison grad student 1972-1976 Chicago
 (Electron paramagnetic resonance and electron proton double resonance in single crystals of lanthanum nicotinate dihydrate dilutely substituted with neodymium)
Robert M. Stroud post-doc 1976-1978 Caltech
Thomas A. Steitz post-doc 1978-1982 Yale
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McKay DB, Xi L, Barthel KK, et al. (2014) Structure and function of steroid receptor RNA activator protein, the proposed partner of SRA noncoding RNA. Journal of Molecular Biology. 426: 1766-85
Hardin JW, Hu YX, McKay DB. (2010) Structure of the RNA binding domain of a DEAD-box helicase bound to its ribosomal RNA target reveals a novel mode of recognition by an RNA recognition motif. Journal of Molecular Biology. 402: 412-27
Wang S, Overgaard MT, Hu Y, et al. (2008) The Bacillus subtilis RNA helicase YxiN is distended in solution. Biophysical Journal. 94: L01-3
Xu X, Wang S, Hu YX, et al. (2007) The periplasmic bacterial molecular chaperone SurA adapts its structure to bind peptides in different conformations to assert a sequence preference for aromatic residues. Journal of Molecular Biology. 373: 367-81
Caruthers JM, Hu Y, McKay DB. (2006) Structure of the second domain of the Bacillus subtilis DEAD-box RNA helicase YxiN. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1191-5
Caruthers JM, Feng Y, McKay DB, et al. (2006) Retention of core catalytic functions by a conserved minimal ribonuclease E peptide that lacks the domain required for tetramer formation. The Journal of Biological Chemistry. 281: 27046-51
Wang S, Hu Y, Overgaard MT, et al. (2006) The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold. Rna (New York, N.Y.). 12: 959-67
Wang S, Fleming RT, Westbrook EM, et al. (2006) Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription. Journal of Molecular Biology. 355: 798-808
Karginov FV, Caruthers JM, Hu Y, et al. (2005) YxiN is a modular protein combining a DEx(D/H) core and a specific RNA-binding domain. The Journal of Biological Chemistry. 280: 35499-505
Bitto E, McKay DB. (2004) Binding of phage-display-selected peptides to the periplasmic chaperone protein SurA mimics binding of unfolded outer membrane proteins. Febs Letters. 568: 94-8
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