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Jon D. Robertus

Affiliations:

University of Texas at Austin, Austin, Texas, U.S.A.

Area:

Biochemistry: Structural Biology, Protein Engineering, And Drug Design

Website:

http://www.cm.utexas.edu/jon_robertus

Google:

Mean distance: 8.19

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Parents

Joseph Kraut	grad student	1972	UCSD
(The X-ray crystallographic study of substrate binding and implications for the mechanism of enzyme action of subtilisin BPN)
Aaron Klug	post-doc	1972-1974	MRC-LMB

Children

William R. Montfort	grad student	1985	UT Austin
Edward M. Marcotte	grad student	1990-1995	UT Austin
Michael Batalia	grad student	1991-1996	UT Austin
John M. Pascal	grad student	2000	UT Austin
Maria M. Svinth	grad student	2000	UT Austin
Kara M. Bortone	grad student	2001	UT Austin
Darcie J. Miller	grad student	2001	UT Austin
Jennifer B. Sadow	grad student	2002	UT Austin
Man Zhang	grad student	2003	UT Austin
Wendi S. Wagner	grad student	2004	UT Austin
Huda S. Suliman	grad student	2006	UT Austin
Shuangluo Xia	grad student	2009	UT Austin

Collaborators

BETA: Related publications

Publications

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Ubhi DK, Robertus JD. (2015) The cobalamin-independent methionine synthase enzyme captured in a substrate-induced closed conformation. Journal of Molecular Biology. 427: 901-9
Ubhi D, Kago G, Monzingo AF, et al. (2014) Structural analysis of a fungal methionine synthase with substrates and inhibitors. Journal of Molecular Biology. 426: 1839-47
Barman S, You L, Chen R, et al. (2014) Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses European Journal of Medicinal Chemistry. 71: 81-90
Wiget PA, Manzano LA, Pruet JM, et al. (2013) Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics. Bioorganic & Medicinal Chemistry Letters. 23: 6799-804
Saito R, Pruet JM, Manzano LA, et al. (2013) Peptide-conjugated pterins as inhibitors of ricin toxin A. Journal of Medicinal Chemistry. 56: 320-9
Pruet JM, Saito R, Manzano LA, et al. (2012) Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A. Acs Medicinal Chemistry Letters. 3: 588-591
Cho EJ, Xia S, Ma LC, et al. (2012) Identification of influenza virus inhibitors targeting NS1A utilizing fluorescence polarization-based high-throughput assay Journal of Biomolecular Screening. 17: 448-459
Wahome PG, Robertus JD, Mantis NJ. (2012) Small-molecule inhibitors of ricin and Shiga toxins. Current Topics in Microbiology and Immunology. 357: 179-207
Jasheway K, Pruet J, Anslyn EV, et al. (2011) Structure-based design of ricin inhibitors. Toxins. 3: 1233-48
Ubhi D, Kavanagh KL, Monzingo AF, et al. (2011) Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Archives of Biochemistry and Biophysics. 513: 19-26

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