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Jon D. Robertus

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Biochemistry: Structural Biology, Protein Engineering, And Drug Design
Website:
http://www.cm.utexas.edu/jon_robertus
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"Jon Robertus"
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SNBCP

Parents

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Joseph Kraut grad student 1972 UCSD
 (The X-ray crystallographic study of substrate binding and implications for the mechanism of enzyme action of subtilisin BPN)
Aaron Klug post-doc 1972-1974 MRC-LMB

Children

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William R. Montfort grad student 1985 UT Austin
Edward M. Marcotte grad student 1990-1995 UT Austin
John M. Pascal grad student 2000 UT Austin
Maria M. Svinth grad student 2000 UT Austin
Kara M. Bortone grad student 2001 UT Austin
Darcie J. Miller grad student 2001 UT Austin
Jennifer B. Sadow grad student 2002 UT Austin
Man Zhang grad student 2003 UT Austin
Wendi S. Wagner grad student 2004 UT Austin
Huda S. Suliman grad student 2006 UT Austin
Shuangluo Xia grad student 2009 UT Austin
BETA: Related publications

Publications

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Ubhi DK, Robertus JD. (2015) The cobalamin-independent methionine synthase enzyme captured in a substrate-induced closed conformation. Journal of Molecular Biology. 427: 901-9
Ubhi D, Kago G, Monzingo AF, et al. (2014) Structural analysis of a fungal methionine synthase with substrates and inhibitors. Journal of Molecular Biology. 426: 1839-47
Robertus JD, Monzingo AF. (2014) The Structure and Action of Ribosome-inactivating Proteins Ribosome-Inactivating Proteins: Ricin and Related Proteins. 111-133
Wiget PA, Manzano LA, Pruet JM, et al. (2013) Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics. Bioorganic & Medicinal Chemistry Letters. 23: 6799-804
Saito R, Pruet JM, Manzano LA, et al. (2013) Peptide-conjugated pterins as inhibitors of ricin toxin A. Journal of Medicinal Chemistry. 56: 320-9
Pruet JM, Saito R, Manzano LA, et al. (2012) Optimized 5-membered heterocycle-linked pterins for the inhibition of Ricin Toxin A. Acs Medicinal Chemistry Letters. 3: 588-591
Wahome PG, Robertus JD, Mantis NJ. (2012) Small-molecule inhibitors of ricin and Shiga toxins. Current Topics in Microbiology and Immunology. 357: 179-207
Jasheway K, Pruet J, Anslyn EV, et al. (2011) Structure-based design of ricin inhibitors. Toxins. 3: 1233-48
Ubhi D, Kavanagh KL, Monzingo AF, et al. (2011) Structure of Candida albicans methionine synthase determined by employing surface residue mutagenesis. Archives of Biochemistry and Biophysics. 513: 19-26
Pruet JM, Jasheway KR, Manzano LA, et al. (2011) 7-Substituted pterins provide a new direction for ricin A chain inhibitors. European Journal of Medicinal Chemistry. 46: 3608-15
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