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William R. Montfort

Biochemistry and Molecular and Cellular Biology University of Arizona, Tucson, AZ 
Protein Structure, Function and Inhibition
"William Montfort"

Mean distance: 8.59


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Jon D. Robertus grad student 1985 UT Austin
 (X-ray crystallographic studies on the toxic protein ricin)
Robert M. Stroud post-doc 1985-1989 UCSF
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Weichsel A, Kievenaar JA, Curry R, et al. (2019) Instability in a Coiled-Coil Signaling Helix is Conserved for Signal Transduction in Soluble Guanylyl Cyclase. Protein Science : a Publication of the Protein Society
Szabo E, Wilk P, Nagy B, et al. (2019) Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants. Human Molecular Genetics
Wales JA, Chen CY, Breci L, et al. (2017) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. The Journal of Biological Chemistry
Montfort WR, Wales J, Weichsel A. (2016) Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor. Antioxidants & Redox Signaling
Sarkar A, Dai Y, Haque MM, et al. (2015) Heat Shock Protein 90 Associates with the Per-Arnt-Sim Domain of Heme-free Soluble Guanylate Cyclase: Implications for Enzyme Maturation. The Journal of Biological Chemistry
Berry RE, Yang F, Shokhireva TK, et al. (2015) Dimerization of nitrophorin 4 at low pH and comparison to the K1A mutant of nitrophorin 1. Biochemistry. 54: 208-20
Gloss AD, Vassão DG, Hailey AL, et al. (2014) Evolution in an ancient detoxification pathway is coupled with a transition to herbivory in the drosophilidae. Molecular Biology and Evolution. 31: 2441-56
Purohit R, Fritz BG, The J, et al. (2014) YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry. 53: 101-14
Purohit R, Weichsel A, Montfort WR. (2013) Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclase. Protein Science : a Publication of the Protein Society. 22: 1439-44
Cheng M, Brookes JF, Montfort WR, et al. (2013) pH-dependent picosecond structural dynamics in the distal pocket of nitrophorin 4 investigated by 2D IR spectroscopy. The Journal of Physical Chemistry. B. 117: 15804-11
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