William R. Montfort

Biochemistry and Molecular and Cellular Biology University of Arizona, Tucson, AZ 
Protein Structure, Function and Inhibition
"William Montfort"


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Jon D. Robertus grad student 1985 UT Austin
 (X-ray crystallographic studies on the toxic protein ricin)
Robert M. Stroud post-doc 1985-1989 UCSF
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Chen CY, Lee W, Renhowe PA, et al. (2020) Solution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051. Protein Science : a Publication of the Protein Society
Weichsel A, Kievenaar JA, Curry R, et al. (2019) Instability in a Coiled-Coil Signaling Helix is Conserved for Signal Transduction in Soluble Guanylyl Cyclase. Protein Science : a Publication of the Protein Society
Szabo E, Wilk P, Nagy B, et al. (2019) Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants. Human Molecular Genetics
Reid DJ, Diesing JM, Miller MA, et al. (2018) MetaUniDec: High-Throughput Deconvolution of Native Mass Spectra. Journal of the American Society For Mass Spectrometry
Berry RE, Yang F, Shokhireva TK, et al. (2015) Dimerization of nitrophorin 4 at low pH and comparison to the K1A mutant of nitrophorin 1. Biochemistry. 54: 208-20
Purohit R, Fritz BG, The J, et al. (2014) YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry. 53: 101-14
Purohit R, Weichsel A, Montfort WR. (2013) Crystal structure of the Alpha subunit PAS domain from soluble guanylyl cyclase. Protein Science : a Publication of the Protein Society. 22: 1439-44
Fritz BG, Roberts SA, Ahmed A, et al. (2013) Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking. Biochemistry. 52: 1568-82
Singh SK, Roberts SA, McDevitt SF, et al. (2011) Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence. The Journal of Biological Chemistry. 286: 37849-57
Ramanathan S, Mazzalupo S, Boitano S, et al. (2011) Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration. Biochemistry. 50: 7787-99
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