Cynthia Wolberger

Johns Hopkins University, Baltimore, MD 
ubiquitination and acetylation, transcription, x-ray crystallography, cryo-EM, biophysical methods
"Cynthia Wolberger"

Mean distance: 7.91


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Stephen C. Harrison grad student 1988 Harvard
 (The structure of a 434 Cro-DNA complex)
Mark Ptashne grad student 1988 Harvard
Carl O. Pabo post-doc Johns Hopkins
Robert M. Stroud post-doc 1987-1989 UCSF
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Worden EJ, Zhang X, Wolberger C. (2020) Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome. Elife. 9
Morgan M, Jbara M, Brik A, et al. (2019) Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage. Methods in Enzymology. 618: 1-27
Nune M, Morgan MT, Connell Z, et al. (2019) FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics. Elife. 8
Jbara M, Laps S, Morgan M, et al. (2018) Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins. Nature Communications. 9: 3154
Bhat S, Hwang Y, Gibson MD, et al. (2018) Hydrazide Mimics for Protein Lysine Acylation to Assess Nucleosome Dynamics and Deubiquitinase Action. Journal of the American Chemical Society
Brickner JR, Soll JM, Lombardi PM, et al. (2017) A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 551: 389-393
Lombardi PM, Matunis MJ, Wolberger C. (2017) RAP80, ubiquitin and SUMO in the DNA damage response. Journal of Molecular Medicine (Berlin, Germany)
Bondalapati S, Eid E, Mali SM, et al. (2017) Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags. Chemical Science. 8: 4027-4034
Chen Z, Jiang H, Xu W, et al. (2017) A Tunable Brake for HECT Ubiquitin Ligases. Molecular Cell. 66: 345-357.e6
Ondracek CR, Frappier V, Ringel AE, et al. (2017) Mutations that Allow SIR2 Orthologs to Function in a NAD(+)-Depleted Environment. Cell Reports. 18: 2310-2319
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