Cynthia Wolberger

Johns Hopkins University, Baltimore, MD 
ubiquitination and acetylation, transcription, x-ray crystallography, cryo-EM, biophysical methods
"Cynthia Wolberger"

Mean distance: 7.91


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Stephen C. Harrison grad student 1988 Harvard
 (The structure of a 434 Cro-DNA complex)
Mark Ptashne grad student 1988 Harvard
Carl O. Pabo post-doc Johns Hopkins
Robert M. Stroud post-doc 1987-1989 UCSF
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Lombardi PM, Haile S, Rusanov T, et al. (2021) The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin. The Journal of Biological Chemistry. 101545
Wolberger C. (2021) How structural biology transformed studies of transcription regulation. The Journal of Biological Chemistry. 100741
Que LT, Morrow ME, Wolberger C. (2020) Comparison of cross-regulation by different OTUB1-E2 complexes. Biochemistry
Worden EJ, Zhang X, Wolberger C. (2020) Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome. Elife. 9
Worden EJ, Wolberger C. (2019) Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases. Current Opinion in Structural Biology. 59: 98-106
Morgan M, Jbara M, Brik A, et al. (2019) Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage. Methods in Enzymology. 618: 1-27
Nune M, Morgan MT, Connell Z, et al. (2019) FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics. Elife. 8
Pasupala N, Morrow ME, Que LT, et al. (2018) OTUB1 non-catalytically stabilizes the E2 ubiquitin-conjugating enzyme UBE2E1 by preventing its autoubiquitination. The Journal of Biological Chemistry
Morgan MT, Wolberger C. (2018) Competition Assay for Measuring Deubiquitinating Enzyme Substrate Affinity. Methods in Molecular Biology (Clifton, N.J.). 1844: 59-70
Morrow ME, Morgan MT, Clerici M, et al. (2018) Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins. Embo Reports
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