☰

Sun Hur

Affiliations: 
Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
Area:
functions and mechanisms of several pattern recognition receptors (PRRs) that specifically recognize viral nucleic acids, such as several Toll like receptors and RIG-I-like helicases
Website:
https://biophysics.fas.harvard.edu/people/sun-hur
Google:
"Sun Hur"
Bio:

http://hurlab.tch.harvard.edu/people/
http://www.fas.harvard.edu/~biophys/Sun_Hur.htm
http://www.idi.harvard.edu/news_events/announcement/sun_hur_named_2010_pew_scholar/

Mean distance: 8.08
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Parents

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Thomas C. Bruice grad student 2003 UC Santa Barbara
 (Theoretical Studies of importance of near attack conformers (NACs) in enzymatic catalysis)
Robert M. Stroud post-doc 2004-2008 UCSF

Children

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Publications

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Hur S, Stroud RM. (2007) How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA. Molecular Cell. 26: 189-203
Hur S, Stroud RM, Finer-Moore J. (2006) Substrate recognition by RNA 5-methyluridine methyltransferases and pseudouridine synthases: a structural perspective. The Journal of Biological Chemistry. 281: 38969-73
Hur S, Newby ZE, Bruice TC. (2004) Transition state stabilization by general acid catalysis, water expulsion, and enzyme reorganization in Medicago savita chalcone isomerase. Proceedings of the National Academy of Sciences of the United States of America. 101: 2730-5
Hur S, Bruice TC. (2003) The near attack conformation approach to the study of the chorismate to prephenate reaction. Proceedings of the National Academy of Sciences of the United States of America. 100: 12015-20
Hur S, Bruice TC. (2003) Just a near attack conformer for catalysis (chorismate to prephenate rearrangements in water, antibody, enzymes, and their mutants). Journal of the American Chemical Society. 125: 10540-2
Hur S, Bruice TC. (2003) Comparison of formation of reactive conformers (NACs) for the Claisen rearrangement of chorismate to prephenate in water and in the E. coli mutase: the efficiency of the enzyme catalysis. Journal of the American Chemical Society. 125: 5964-72
Hur S, Kahn K, Bruice TC. (2003) Comparison of formation of reactive conformers for the SN2 displacements by CH3CO2- in water and by Asp124-CO2- in a haloalkane dehalogenase. Proceedings of the National Academy of Sciences of the United States of America. 100: 2215-9
Hur S, Bruice TC. (2003) Enzymes do what is expected (chalcone isomerase versus chorismate mutase). Journal of the American Chemical Society. 125: 1472-3
Hur S, Bruice TC. (2002) Molecular dynamic study of orotidine-5'-monophosphate decarboxylase in ground state and in intermediate state: a role of the 203-218 loop dynamics. Proceedings of the National Academy of Sciences of the United States of America. 99: 9668-73
Hur S, Bruice TC. (2002) The mechanism of cis-trans isomerization of prolyl peptides by cyclophilin. Journal of the American Chemical Society. 124: 7303-13
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