Pascal F. Egea

Affiliations: 
Biological Chemistry University of California, Los Angeles, Los Angeles, CA 
Area:
Membrane Protein Structure, Targeting and, Assembly
Website:
http://portal.ctrl.ucla.edu/biological-chemistry/institution/personnel?personnel_id=949829
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"Pascal Egea"
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Publications

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AhYoung AP, Koehl A, Vizcarra CL, et al. (2015) Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum. Protein Science : a Publication of the Protein Society
AhYoung AP, Koehl A, Cascio D, et al. (2015) Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design. Protein Science : a Publication of the Protein Society
AhYoung AP, Jiang J, Zhang J, et al. (2015) Conserved SMP domains of the ERMES complex bind phospholipids and mediate tether assembly. Proceedings of the National Academy of Sciences of the United States of America. 112: E3179-88
Gold DA, Kaplan AD, Lis A, et al. (2015) The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole. Cell Host & Microbe. 17: 642-52
Peng M, Cascio D, Egea PF. (2015) Crystal structure and solution characterization of the thioredoxin-2 from Plasmodium falciparum, a constituent of an essential parasitic protein export complex. Biochemical and Biophysical Research Communications. 456: 403-9
Egea PF, Muller-Steffner H, Kuhn I, et al. (2012) Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One. 7: e34918
Korennykh AV, Egea PF, Korostelev AA, et al. (2011) Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1. Bmc Biology. 9: 48
Korennykh AV, Korostelev AA, Egea PF, et al. (2011) Structural and functional basis for RNA cleavage by Ire1. Bmc Biology. 9: 47
Brown CM, Ray M, Eroy-Reveles AA, et al. (2011) Peptide length and leaving-group sterics influence potency of peptide phosphonate protease inhibitors. Chemistry & Biology. 18: 48-57
Egea PF, Stroud RM. (2010) Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes. Proceedings of the National Academy of Sciences of the United States of America. 107: 17182-7
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