☰ Chemistry Tree

Paul H. Weigel

Affiliations:

Biochemistry and Molecular Biology

University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States

Area:

Structure-function of Glycosaminoglycan Receptors and Hyaluronic Acid Synthases and their roles in human diseases

Website:

http://www.oumedicine.com/department-of-biochemistry-and-molecular-biology/faculty/paul-h-weigel-ph-d-

Google:

Bio:

http://www.oumedicine.com/docs/ou-medicine/weigel-nihbio.pdf?sfvrsn=0

Mean distance: 8.75

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Parents

Paul T. Englund	grad student	1975	Johns Hopkins
(Studies on DNA replication in Escherichia Coli)
Yuan Chuan Lee	post-doc	1975-1978	Johns Hopkins
Saul Roseman	post-doc	1975-1978	Johns Hopkins

Children

Jasper H. Yik	grad student	2002	University of Oklahoma Health Sciences Center
Andria P. Medina	grad student	2009	University of Oklahoma Health Sciences Center
Madhu S. Pandey	grad student	2012	University of Oklahoma Health Sciences Center
Franklin A. Hays	post-doc	2009-2010	University of Oklahoma Health Sciences Center

Collaborators

BETA: Related publications

Publications

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Weigel PH. (2020) Systemic Glycosaminoglycan Clearance by HARE/Stabilin-2 Activates Intracellular Signaling. Cells. 9
Wei W, Faubel JL, Selvakumar H, et al. (2019) Self-regenerating giant hyaluronan polymer brushes. Nature Communications. 10: 5527
Weigel PH. (2019) Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2. Biomolecules. 9
Srivastava T, Diba P, Dean JM, et al. (2018) A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors. The Journal of Clinical Investigation
Weigel PH. (2017) Planning, evaluating, and vetting receptor signaling studies to assesshyaluronan size-dependence and specificity. Glycobiology
Weigel PH, Baggenstoss BA. (2017) What is special about 200 kDa hyaluronan that activates hyaluronan receptor signaling? Glycobiology
Weigel PH, Baggenstoss BA, Washburn JL. (2017) HYALURONAN SYNTHASE ASSEMBLES HYALURONAN ON A [GLcNAc(β1,4)]n-GLcNAc(α1→)UDP PRIMER AND HYALURONAN RETAINS THIS RESIDUAL CHITIN OLIGOMER AS A CAP AT THE NONREDUCING END. Glycobiology
Baggenstoss BA, Harris EN, Washburn JL, et al. (2016) HYALURONAN SYNTHASE CONTROL OF SYNTHESIS RATE AND HYALURONAN PRODUCT SIZE ARE INDEPENDENT FUNCTIONS DIFFERENTIALLY AFFECTED BY MUTATIONS IN A CONSERVED TANDEM B-X7-B MOTIF. Glycobiology
Pandey MS, Miller CM, Harris EN, et al. (2016) Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs. Plos One. 11: e0154124
Weigel PH. (2015) Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell Exterior. International Journal of Cell Biology. 2015: 367579

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