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Paul H. Weigel

Affiliations: 
Biochemistry and Molecular Biology University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Structure-function of Glycosaminoglycan Receptors and Hyaluronic Acid Synthases and their roles in human diseases
Website:
http://www.oumedicine.com/department-of-biochemistry-and-molecular-biology/faculty/paul-h-weigel-ph-d-
Google:
"Paul Weigel"
Bio:

http://www.oumedicine.com/docs/ou-medicine/weigel-nihbio.pdf?sfvrsn=0

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Publications

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Srivastava T, Diba P, Dean JM, et al. (2018) A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors. The Journal of Clinical Investigation
Baggenstoss BA, Harris EN, Washburn JL, et al. (2016) HYALURONAN SYNTHASE CONTROL OF SYNTHESIS RATE AND HYALURONAN PRODUCT SIZE ARE INDEPENDENT FUNCTIONS DIFFERENTIALLY AFFECTED BY MUTATIONS IN A CONSERVED TANDEM B-X7-B MOTIF. Glycobiology
Pandey MS, Miller CM, Harris EN, et al. (2016) Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs. Plos One. 11: e0154124
Weigel PH. (2015) Hyaluronan Synthase: The Mechanism of Initiation at the Reducing End and a Pendulum Model for Polysaccharide Translocation to the Cell Exterior. International Journal of Cell Biology. 2015: 367579
Simpson MA, de la Motte C, Sherman LS, et al. (2015) Advances in Hyaluronan Biology: Signaling, Regulation, and Disease Mechanisms. International Journal of Cell Biology. 2015: 690572
Pandey MS, Harris EN, Weigel PH. (2015) HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs. International Journal of Cell Biology. 2015: 524707
Weigel PH, West CM, Zhao P, et al. (2015) Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end. Glycobiology. 25: 632-43
Pandey MS, Weigel PH. (2014) A hyaluronan receptor for endocytosis (HARE) link domain N-glycan is required for extracellular signal-regulated kinase (ERK) and nuclear factor-κB (NF-κB) signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate, or acetylated low density lipoprotein (LDL). The Journal of Biological Chemistry. 289: 21807-17
Pandey MS, Weigel PH. (2014) Hyaluronic acid receptor for endocytosis (HARE)-mediated endocytosis of hyaluronan, heparin, dermatan sulfate, and acetylated low density lipoprotein (AcLDL), but not chondroitin sulfate types A, C, D, or E, activates NF-κB-regulated gene expression. The Journal of Biological Chemistry. 289: 1756-67
Weigel PH, Padgett-McCue AJ, Baggenstoss BA. (2013) Methods for measuring Class I membrane-bound hyaluronan synthase activity. Methods in Molecular Biology (Clifton, N.J.). 1022: 229-47
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