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Jonathan B. Cohen, Ph.D.

Affiliations: 
Massachusetts General Hospital, Boston, MA 
 1975-1982 Pharmacology Harvard Medical School, Boston, MA, United States 
 1982-1992 Anatomy and Neurobiology Washington University School of Medicine, St. Louis, MO, United States 
 1992- Neurobiology Harvard Medical School, Boston, MA, United States 
Area:
nicotinic acetylcholine receptors (AChR) and GABAa receptors
Website:
http://www.fas.harvard.edu/~biophys/Jonathan_B_Cohen.htm
Google:
"Jonathan B. Cohen"
Bio:

http://www.hms.harvard.edu/dms/neuroscience/fac/cohen.php
http://www.hms.harvard.edu/bss/neuro/cohen/
http://neuro.med.harvard.edu/faculty/cohen.html

Mean distance: 13.68 (cluster 11)
 
SNBCP
Cross-listing: Neurotree

Parents

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Edgar Bright Wilson, Jr. grad student 1972 Harvard
 (Microwave-microwave double resonance investigations of collisional transfer of rotational energy)
Jean-Pierre Changeux post-doc Institut Pasteur

Children

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Richard Neubig grad student 1980 Harvard Medical School (Neurotree)
Marcus L. Ware grad student 2000 Harvard (Neurotree)
Jonathan C. Trinidad grad student 2003 Harvard (Neurotree)
Michael J. Bianchetta grad student 2004 Harvard (Neurotree)
Filbert H. Hong grad student 2004 Harvard (Neurotree)
Laura M. Magnotti grad student 2010 Harvard (Neurotree)
Steen E. Pedersen post-doc 1984-1989 Washington University
Marc Bartoli post-doc 1999-2001 Harvard Medical School (Neurotree)
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Publications

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McGrath M, Hoyt H, Pence A, et al. (2020) Competitive Antagonism of Etomidate Action by Diazepam. Anesthesiology. 133: 583-594
McGrath M, Hoyt H, Pence A, et al. (2020) Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology
Jayakar SS, Chiara DC, Zhou X, et al. (2020) Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry
Shalabi AR, Yu Z, Zhou X, et al. (2020) A potent photoreactive general anesthetic with novel binding site selectivity for GABA receptors. European Journal of Medicinal Chemistry. 194: 112261
Yu Z, Chiara DC, Savechenkov PY, et al. (2019) A photoreactive analog of allopregnanolone enables identification of steroid-binding sites in a nicotinic acetylcholine receptor. The Journal of Biological Chemistry
Yu Z, Savechenkov PY, Bruzik KS, et al. (2019) Identifying Steroid Binding Sites in a Nicotinic Acetylcholine Receptor (nAChR) with a Photoreactive Analog of Alphaxalone Biophysical Journal. 116: 395a
Chiara DC, Wu B, Zhou X, et al. (2019) Identification of a High-Affinity Neurosteroid Binding Site in Human Alpha1Beta3 GabaAR using a Photoreactive Thdoc Analog Biophysical Journal. 116: 392a
Jayakar SS, Zhou X, Wu B, et al. (2019) Pharmacological Selectivity of a Steroid Binding Site at the Beta+-Alpha− Interface of Alpha1 Beta3 Gaba-A Receptors Biophysical Journal. 116: 392a
Wu B, Jayakar SS, Zhou X, et al. (2018) Inhibitable photolabeling by neurosteroid diazirine analog in the β3-Subunit of human hetereopentameric type A GABA receptors. European Journal of Medicinal Chemistry. 162: 810-824
McGrath M, Yu Z, Jayakar SS, et al. (2018) Etomidate and Etomidate Analog Binding and Positive Modulation of γ-Aminobutyric Acid Type A Receptors: Evidence for a State-dependent Cutoff Effect. Anesthesiology
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