Shan Zha, Ph.D.

Affiliations: 
1998-2004 Pharmacology and Molecular Sciences Johns Hopkins University, Baltimore, MD 
 2004-2009 Molecular Genetics Harvard - Boston Children's Hospital 
 2009- Institute for Cancer Genetics Columbia University College of Physicians and Surgeons, New York, NY, United States 
Area:
DNA repair, Oncology, Molecular Biology, Pharmacology
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Parents

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William B. Isaacs grad student 1998-2004 Johns Hopkins
 (Cyclooxygenase-2 and alpha-methylacyl-CoA racemase in prostate cancer.)
Frederick W. Alt post-doc 2004-2009 Harvard - Boston Children's Hospital
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Publications

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Milanovic M, Shao Z, Estes VM, et al. (2021) FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis. Journal of Immunology (Baltimore, Md. : 1950)
Milanovic M, Houghton LM, Menolfi D, et al. (2020) The cancer-associated ATM R3008H mutation reveals the link between ATM activation and its exchange. Cancer Research
Wang XS, Zhao J, Wu-Baer F, et al. (2020) CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining. Proceedings of the National Academy of Sciences of the United States of America
Shao Z, Lee BJ, Rouleau-Turcotte É, et al. (2020) Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo. Nucleic Acids Research
Crowe JL, Wang XS, Shao Z, et al. (2020) DNA-PKcs phosphorylation at the T2609 cluster alters the repair pathway choice during immunoglobulin class switch recombination. Proceedings of the National Academy of Sciences of the United States of America
Wang XS, Lee BJ, Zha S. (2020) The recent advances in non-homologous end-joining through the lens of lymphocyte development. Dna Repair. 94: 102874
Liu X, Liu T, Shang Y, et al. (2020) ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells. Cell Research
Tao Y, Li M, Liu X, et al. (2020) Dual-color plasmonic nanosensor for radiation dosimetry. Acs Applied Materials & Interfaces
Shao Z, Flynn RA, Crowe JL, et al. (2020) DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature
Jiang W, Estes VM, Wang XS, et al. (2019) Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination. Journal of Immunology (Baltimore, Md. : 1950)
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